Abstract 97: Acute Ischemic Stroke Despite Anticoagulant Use: The Neuro-AFib Study

Stroke, Volume 55, Issue Suppl_1, Page A97-A97, February 1, 2024. Background:Acute ischemic stroke (AIS) admissions in patients with atrial fibrillation (AF) using anticoagulants (AIS-despite-AC) are commonly seen in stroke units but data on their frequency, causes, and outcomes are scarce.Methods:The Neuro-AFib study is a multicenter effort geared toward elucidating the causes and consequences of strokes in a contemporary AF cohort. Detailed clinical, laboratory and multimodal imaging data from known AF patients consecutively admitted to 20 stroke centers with an IS between 1/2018-12/2019 were used to define characteristics of AIS-despite-AC and compared to AIS-off-AC.Results:Out of 4456 patients with known AF prior to the AIS, 2051 (46%) were using anticoagulants. Patients who had AIS-despite-AC were younger (76.8+11 vs 77.8+12, p=0.007), had higher mean CHA2DS2-VASc scores (4.57+1.7 vs 4.21+1.7, p

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Febbraio 2024