Association of Net Water Uptake With Catastrophic Functional Outcome After Thrombectomy in Patients With Large Infarcts
Stroke, Ahead of Print. BACKGROUND:This study aimed to investigate whether net water uptake (NWU) is associated with 3-month catastrophic functional outcome (modified Rankin Scale score, 5–6) and to develop predictive models with preprocedural factors, including NWU, in patients with large infarcts…
Observations from ID and Beyond: Hot Takes from IDWeek: CDC, COVID, and Two Doses of Dalbavancin
Dr. Paul Sax shares a conversation held during IDWeek, in HIV and ID Observations.
[Articles] Recipient-focused interventions to increase vaccine uptake in high and upper-middle income countries: a systematic review and network meta-analysis
Vaccination programmes in high and upper-middle income countries should prioritise ensuring vaccines are accessible, convenient, and affordable for the recipient. Efforts should be directed towards further investigating and optimising access and affordability interventions. The possible negative im…
Linee guida di pratica clinica per il trattamento dell’ipoparatiroidismo cronico negli adulti
Endocrinologia e Malattie MetabolicheLa Società Europea di Endocrinologia (ESE) ha pubblicato una linea guida clinica rivista per il trattamento dell’ipoparatiroidismo...
COVID-19 mRNA Vaccines Aid Immune Checkpoint Inhibitor Cancer Therapy
Receiving a vaccine that is not directed at tumor antigens can improve survival.
Educational Strategies for Clinical Supervision of Artificial Intelligence Use
New England Journal of Medicine, Volume 393, Issue 19, Page 1965-1968, November 13, 2025.
A Mammarenavirus Close to Lassa Virus in a Patient with Meningoencephalitis
New England Journal of Medicine, Volume 393, Issue 19, Page 1960-1962, November 13, 2025.
Sudden Cardiac Death in the U.S.: 20-Year Trends
Rates were decreasing steadily until the COVID-19 pandemic.
ETV5-S100A9 feed-forward loop connecting HCC and MDSCs to shape the immunosuppressive tumour microenvironment
Hepatocellular carcinoma (HCC), the most common form of primary liver cancer, is a leading cause of cancer-related deaths worldwide, accounting for approximately 800 000 deaths annually. Treatment options for unresectable, advanced-stage HCC are very limited. For decades, tyrosine kinase inhibitors…
Anticoagulation in colorectal ESD: implications for bleeding risk management
We read with great interest the recent multicentre randomised controlled trial (RCT) by Miyakawa et al,1 which demonstrated a significant reduction in delayed bleeding after colorectal endoscopic submucosal dissection (ESD) through prophylactic clip closure. The authors are to be commended for cond…
Response by Zile et al to Letter Regarding Article, “Effects of Tirzepatide on the Clinical Trajectory of Patients With Heart Failure, Preserved Ejection Fraction, and Obesity”
Circulation, Volume 152, Issue 19, Page e374-e375, November 11, 2025.
Letter by Zhao et al Regarding Article, “Effects of Tirzepatide on the Clinical Trajectory of Patients With Heart Failure, Preserved Ejection Fraction, and Obesity”
Circulation, Volume 152, Issue 19, Page e372-e373, November 11, 2025.
Possible Evolutionary Origins of Atherosclerosis: Suggestive Evidence From Ancient to Modern Populations
Circulation, Volume 152, Issue 19, Page 1323-1325, November 11, 2025.
Correction to: 2025 ACC/AHA/ACEP/NAEMSP/SCAI Guideline for the Management of Patients With Acute Coronary Syndromes: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines
Circulation, Volume 152, Issue 19, Page e402-e402, November 11, 2025.
Correction to: 2025 AHA/ACC/AANP/AAPA/ABC/ACCP/ACPM/AGS/AMA/ASPC/NMA/PCNA/SGIM Guideline for the Prevention, Detection, Evaluation and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines
Circulation, Volume 152, Issue 19, Page e403-e403, November 11, 2025.
Correction to: Fast Degradation of MecciRNAs by SUPV3L1/ELAC2 Provides a Novel Opportunity to Tackle Heart Failure With Exogenous MecciRNA
Circulation, Volume 152, Issue 19, Page e404-e404, November 11, 2025.
