Abstract WP278: Metabolic Control of Neuroinflammation: The Role of Irg1/Itaconate in Intracerebral Hemorrhage
Stroke, Volume 57, Issue Suppl_1, February 1, 2026. Purpose:Secondary brain injury following intracerebral hemorrhage (ICH) is amplified by metabolic reprogramming of resident microglia and infiltrating leukocytes in the peri-hematomal region. We previously identified itaconate—a metabolite generat…
Abstract WP275: ICU and Beyond, Does Closing the loop for the Neuro ICU team have a postitive impact
Stroke, Volume 57, Issue Suppl_1, February 1, 2026. Background:As a comprehensive stroke certified center, the success of patient care relies on a multidisciplinary team approach. The acute phase of stroke care involves the stroke team and the Neuro critical care (NCC) team. Post discharge from the…
Abstract WP276: Resource Utilization After Mechanical Thrombectomy: Is ICU Care Required for All Patients?
Stroke, Volume 57, Issue Suppl_1, February 1, 2026. Background:Mechanical thrombectomy (MT) is the standard of care for qualifying patients with acute ischemic stroke (AIS). Minimal post-procedural guidelines often result in patients being admitted to the intensive care unit (ICU) for 24 hours, eve…
Abstract WP047: Incidental Cerebral Aneurysms in Patients with Cervical Artery Dissection
Stroke, Volume 57, Issue Suppl_1, February 1, 2026. Background:Patients with cervical artery dissection (CAD) have a higher prevalence of cerebral aneurysms, likely due to underlying vasculopathies. Understanding risk factors and outcomes in this population may inform screening and management strat…
Abstract DP253: From Click to Clot Removal: APP-Driven Speed in Stroke Treatment
Stroke, Volume 57, Issue Suppl_1, February 1, 2026. Background:Timely intervention is critical in acute ischemic stroke, particularly for patients needing endovascular therapy. Delays in team activation and fragmented communication can hinder door-to-device times, impacting outcomes and performance…
Abstract DP008: Trends in Vascular Risk Factor Control Among U.S. Adults with Prior Stroke: 1999-2018
Stroke, Volume 57, Issue Suppl_1, February 1, 2026. Background:Management of modifiable risk factors is the mainstay for the prevention of recurrent stroke. Our objective was to investigate trends in vascular risk factor (hyperglycemia, hyperlipidemia, hypertension, and smoking) control among commu…
Abstract DP010: Predictors of Major Adverse Cardiovascular Events After Transient Ischemic Attack: A Multi-State Analysis
Stroke, Volume 57, Issue Suppl_1, February 1, 2026. Background:Patients with transient ischemic attack (TIA) are at high risk of subsequent vascular complications, yet large-scale, population-based analyses of risk factors for major adverse cardiovascular events (MACE) are limited. We evaluated dem…
Abstract DP266: Lysosome-Mitochondria Temporal and Spatial Regulation of Zinc Aggregation: A Novel Mechanistic Pathway in Ischemic Stroke
Stroke, Volume 57, Issue Suppl_1, February 1, 2026. Introduction:Ischemia stroke is the second leading cause of death and disability globally. Mitochondria play a pivotal role in determining ischemia stroke outcomes. We have confirmed that zinc increased immediately after reperfusion in ischemic pe…
Abstract DP025: Differential Actionable Information Yield and Prognostic Value of Perfusion Imaging Ischemic Core Volumes Among EVT Patients with Good and Poor Collaterals – A Secondary Analysis of SELECT2 and SELECT Trial
Stroke, Volume 57, Issue Suppl_1, February 1, 2026. Introduction:Collateral status and perfusion imaging both capture downstream flow in the occluded territory for patients with acute ischemic stroke. Collateral status can be obtained from CT/MR Angiography, which is part of the standard workflow. …
Abstract WP067: High prevalence of non critical coronary artery stenosis on CT coronary angiography in stroke patients
Stroke, Volume 57, Issue Suppl_1, February 1, 2026. Introduction:Both cerebrovascular and coronary artery disease are leading causes of mortality and share common vascular risk factors such as hypertension, diabetes, hypercholesterolemia and smoking. Following a stroke, there is an approximate 25% …
Abstract WP030: Association of prehospital treatment duration with the efficacy of remote ischemic conditioning in the RESIST trial
Stroke, Volume 57, Issue Suppl_1, February 1, 2026. Background:Remote ischemic conditioning (RIC) initiated in the prehospital setting did not improve functional outcome at 90 days in patients with acute stroke in the RESIST trial. Trials of other neuroprotective therapies have identified the durat…
Sport antidoto contro ansia e depressione, fa bene anche vederlo in poltrona: “Prescriverlo come i farmaci”
Non è solo una questione di muscoli, ma di cervello, sinapsi e neurotrasmettitori. La Società Italiana di Neuropsicofarmacologia (Sinpf) lancia un appello agli specialisti: prescrivere l’attività fisica con la stessa…
In Germania salari più alti, ma Sanità sotto stress: “La mia esperienza di medico italiano all’estero”
Ho letto con interesse le parole del Governatore Fabio Panetta sul capitale umano e sul divario retributivo tra giovani laureati italiani e tedeschi. È vero: in Germania si guadagna di…
Association of Pre-Fontan Hemodynamics With Long-Term Outcomes After Fontan Palliation: A Study From the Pediatric Cardiac Care Consortium
Circulation, Ahead of Print. BACKGROUND:Long-term outcomes after Fontan vary widely. Although pre-Fontan hemodynamics predict early failure, their association with long-term outcomes remains unclear. We hypothesized that pre-Fontan hemodynamics predict long-term risk of death or transplantation.MET…
Sei workaholic? Come riconoscere la dipendenza da lavoro o workaholism
Stress da lavoro – Sei workaholic? Scopri cos’è la dipendenza da lavoro (workaholism), l’incapacità di separare lavoro e vita privata, le conseguenze sulla salute.
Correction to: Heart Stress and Blood Pressure Management in Older Adults: Post Hoc Analysis of the ASPREE Trial
Circulation, Volume 153, Issue 3, Page e20-e20, January 20, 2026.
