Linee guida ESC per la gestione delle cardiopatie congenite dell’adulto
CardiovascolareLa Società Europea di Cardiologia (ESC) ha pubblicato nel 2020 un aggiornamento delle linee guida per la gestione delle cardiopatie...
[Articles] Major adverse cardiovascular events after liver transplantation: a population cohort analysis of English transplant centres
MACE and cardiovascular death are uncommon within the first-year post LT in England. However, liver transplant recipients with non-fatal MACE have inferior long-term survival. Further work is warranted to determine the best strategy to mitigate cardiac risk stratification for LT candidates and evid…
ESC 2025. Focused Update delle linee guida ESC/EAS sulla gestione delle dislipidemie (disordini del metabolismo dei lipidi)
Endocrinologia e Malattie MetabolicheAutore/Fonte: European Society of Cardiology (ESC). European Atherosclerosis Society (EAS) Società Europea di Cardiologia La European...
Inhibition of Annexin A2 Facilitates PHB2-Mediated Mitophagy in Cardiomyocytes to Alleviate Cardiac Injury and Remodeling After Infarction
Circulation, Ahead of Print. BACKGROUND:Mitophagy is critically involved in cardiac injury and repair after myocardial infarction (MI), whereas the annexin A family plays an important role in mitophagy. However, the intrinsic molecular underpinnings that orchestrate the homeostasis of mitophagy in …
GRSF1 Protects Against Heart Failure by Maintaining BCAA Homeostasis
Circulation, Ahead of Print. BACKGROUND:Imbalances in cardiac branched-chain amino acid (BCAA) metabolism and mitochondrial homeostasis are implicated in the onset and development of heart failure. However, the mechanisms triggering the downregulation of cardiac BCAA metabolism in heart failure rem…
Myocardial Recovery With Mechanical Circulatory Support Is Linked to Alternative Splicing and Subcellular Localization of CAMK2D
Circulation, Ahead of Print. BACKGROUND:Cardiac reverse remodeling occurs in a small subset of patients with heart failure treated with guideline-directed therapies. This phenomenon, which is defined by reduced ventricular dilatation and improved systolic function, is most common in patients receiv…
Algoritmo terapeutico per la Miastenia Gravis (MG)
Flow-chart TerapeuticheRiferimenti: Diagnosis Flowchart for Myasthenia Gravis – EuroMyasthenia; International Consensus Guidance for MG 2020 (MGFA):...
Algoritmo diagnostico per la Miastenia Gravis (MG)
Flow-chart DiagnosticheRiferimenti: Diagnosis Flowchart for Myasthenia Gravis – EuroMyasthenia; International Consensus Guidance for MG 2020 (MGFA):...
[Review] Outcome reporting for liver transplantation machine perfusion studies: a systematic review
There is significant variability in post-transplant complications reporting by LT with MP studies. Uniform definitions and standardized guidelines are critical to allow rigorous comparison of different perfusion techniques and other future innovations.
Revisione su diagnosi e gestione della gammopatia monoclonale di significato indeterminato
EmatologiaLa gammopatia monoclonale di significato indeterminato (MGUS) è una condizione precursore frequente, presente in circa il 5% degli adulti,...
Gestione e significato clinico della paraproteinemia monoclonale: aggiornamento sulle raccomandazioni per la MGUS
EmatologiaLa paraproteinemia monoclonale, nella sua forma più comune di gammopatia monoclonale di significato indeterminato (MGUS), è una...
Engineered Regulatory T Lymphocytes Promote Infarcted Heart Repair
Circulation, Ahead of Print. BACKGROUND:Myocardial infarction (MI) initiates a dysregulated healing process characterized by excessive fibrosis and unresolved inflammation, resulting in suboptimal cardiac repair in clinical settings. Regulatory T lymphocytes (Tregs) naturally orchestrate cardiac re…
Gestione della malattia renale cronica con nuovi farmaci nefroprotettivi: linea guida
NefrologiaQueste linee guida, sviluppate dalla Società Italiana di Nefrologia (SIN) in collaborazione con altre associazioni mediche,...
