Prevenzione, diagnosi e gestione della BPCO (GOLD 2026)
BPCOPresentato l’aggiornamento 2026 delle linee guida del Global Initiative for Chronic Obstructive Lung Disease (GOLD) durante la...
Adesione ai trattamenti ASA + Statine in medicina generale: evidenze da uno studio italiano real-world
Notizie dalla RicercaQuesto studio real-world basato mostra un punto molto chiaro: i pazienti che assumono ASA e statina come due farmaci separati hanno livelli...
[Articles] Effect of subcutaneous lidocaine–hydroxypropyl-β-cyclodextrin (HP-β-CD) on quality of life in patients with post-COVID condition: a 36-week observational interrupted time series study
Subcutaneous lidocaine–HP-β-CD was associated with significantly improved quality of life and symptom burden in patients with post–COVID. This home-administered intervention offers a scalable and potentially disease-modifying approach for a disabling condition with no approved treatment to date.
CMAJ: nuove linee guida sulla prevenzione dell’HIV prima e dopo l’esposizione
HIVSono ora disponibili trattamenti pre-esposizione multipla (PrEP) e post-esposizione (PEP) per prevenire l’infezione da HIV....
Pragmatic Comparative Effectiveness of Primary Care Treatments for PTSD
This randomized clinical trial investigates the effectiveness of brief trauma-focused psychotherapy compared with that of selective serotonin reuptake inhibitors for the treatment of posttraumatic stress disorder in primary care.
Error in Abstract
In the Original Investigation titled “Pragmatic Comparative Effectiveness of Primary Care Treatments for Posttraumatic Stress Disorder: a Randomized Clinical Trial,” published online October 15, 2025, there was an error in the Results of the Abstract. The phrase “11 of 352 patients (31.5%) randomiz…
[Articles] Efficacy of a school-based, universal prevention programme for depression and anxiety in adolescents (OurFutures Mental Health): a two-arm cluster-randomised controlled trial
OurFutures Mental Health may be an efficacious intervention to improve mental health knowledge and prevent anxiety symptoms among adolescents in the short-term. Limitations of this trial include high participant attrition and withdrawal of several schools post-randomisation, limiting generalisabili…
Violenza sulle donne: oltre la metà delle vittime sviluppa disturbo da stress post traumatico
Violenza sulle donne – Violenza sulle donne: oltre 6,4 milioni di vittime in Italia. Le conseguenze? PTSD, depressione e rischio recidiva nei risultati del progetto EpiWE.
Gestione farmacologica della malattia di Crohn da moderata a grave: linea guida
Gastroenterologia ed EpatologiaL’American Gastroenterological Association (AGA) ha pubblicato nuove linee guida cliniche per la gestione farmacologica...
WHO: linee guida sul diabete in gravidanza
Endocrinologia e Malattie MetabolicheQueste linee guida pubblicate dal WHO (World Health Organization) forniscono consigli per le donne in gravidanza con...
Linee guida cliniche ACG: diagnosi e gestione delle condizioni premaligne gastriche
Gastroenterologia ed EpatologiaLe condizioni premalignanti gastriche (GPMC) sono comuni e includono la gastrite atrofica, la metaplasia intestinale gastrica, la displasia...
Should Blood Pressure Targets Differ for Frail and Nonfrail Adults?
In a post hoc analysis of a large randomized trial, frail and nonfrail patients experienced similar benefits and harms of intensive BP control.
Lo stress può alterare il flusso sanguigno nel cervello
Notizie dalla RicercaI ricercatori della Pennsylvania State University hanno scoperto che un raro neurone sensibile allo stress, chiamato neurone nNOS di...
Linee guida di pratica clinica per il trattamento dell’ipoparatiroidismo cronico negli adulti
Endocrinologia e Malattie MetabolicheLa Società Europea di Endocrinologia (ESE) ha pubblicato una linea guida clinica rivista per il trattamento dell’ipoparatiroidismo...
ETV5-S100A9 feed-forward loop connecting HCC and MDSCs to shape the immunosuppressive tumour microenvironment
Hepatocellular carcinoma (HCC), the most common form of primary liver cancer, is a leading cause of cancer-related deaths worldwide, accounting for approximately 800 000 deaths annually. Treatment options for unresectable, advanced-stage HCC are very limited. For decades, tyrosine kinase inhibitors…
Intrahepatic donor microbiota-based metataxonomic signature detected in organ preservation solution enables prediction of short-term liver transplant outcomes
Background
Liver transplantation (LT) remains hampered by post-transplant complications. While gut microbiota dysbiosis has been linked to transplant outcomes, the role of the intrahepatic graft’s native microbiota remains unexplored.
Objective
To characterise the microbial profile detected in orga…
