Diritti dell’infanzia: all’aria aperta o in gruppo, ecco perché giocare fa bene alla salute dei bambini
Rincorrersi, saltare, costruire capanne, inventare storie con gli amici: giocare è qualcosa che i bambini fanno ogni giorno, in modo spontaneo. Ma al di là del divertimento, giocare è davvero…
CD4+ Tregs Regulate Heart Growth and Regeneration Through MRG15/TIP60-Mediated Epigenomic Remodeling in Proliferating Cardiomyocytes
Circulation, Ahead of Print. BACKGROUND:Cardiovascular disease remains a leading cause of mortality globally, with the adult mammalian heart exhibiting limited regenerative capacity. The chromatin regulatory network plays a crucial role in the dynamic changes in gene expression that orchestrate the…
Testing for Primary Aldosteronism Underutilized Following Stroke: A Multicenter Cohort Study
Stroke, Ahead of Print. BACKGROUND:Primary aldosteronism, the most common endocrine cause of hypertension, is associated with an increased risk of stroke compared with essential hypertension. Targeted treatment with mineralocorticoid receptor antagonists, or surgical resection of an aldosterone-pro…
Così riscaldamento globale e inquinamento indeboliscono spermatozoi e fertilità maschile
L’Italia è uno dei Paesi con il tasso di natalità più bassi al mondo. Un dato allarmante che trova radici in molteplici fattori socioeconomici e culturali, ma anche in cause…
[Articles] Natural, unnatural, and cause-specific mortality among current psychiatric inpatients: a systematic review and meta-analysis
Mortality rates in psychiatric hospitals are highly heterogeneous but have been falling over time. Most inpatient deaths have a natural cause. Our findings suggest a need for primary research examining the demographic and diagnostic associations with inpatient mortality, while underscoring the oppo…
The Disease Burden of Helicobacter pylori Beyond Gastric Cancer: Quantifying the Forgotten Potential Benefits of Mass Eradication
Treatment of the bacterial infection Helicobacter pylori is often aimed at preventing gastric cancer, but also prevents other diseases, such as ulcers. Although these diseases are rarely lethal, they often cause discomfort and, therefore, should be considered in the decision whether to screen-and-t…
Diabete: il video completo su sintomi, esami, cura e prevenzione
Diabete – Sai riconoscere i segnali del diabete? Scopri come prevenirlo e gestirlo nel video della Dr.ssa Contri che ti spiega tutto sulla malattia: tipi, sintomi, cause.
Boom globale di ipertensione nei bambini: raddoppia in 20 anni
Negli ultimi vent’anni si è registrato un aumento allarmante dell’ipertensione nei bambini e negli adolescenti di tutto il mondo. Una recente analisi pubblicata sulla rivista The Lancet Child & Adolescent…
Harnessing the Power of Low-Intensity Focused Ultrasound Stimulation in Stroke: Modulating Immune Response
Stroke, Ahead of Print. Stroke remains a leading cause of death and disability worldwide, with both ischemic and hemorrhagic subtypes triggering complex inflammatory cascades that exacerbate neuronal damage and impede recovery. Despite significant advances in understanding stroke pathophysiology, t…
Retraction Notice to: “A Rare Cause of Peri-esophageal Cystic Lesion”
This article has been retracted: please see Elsevier policy on article withdrawal (https://www.elsevier.com/about/policies-and-standards/article-withdrawal).This article has been retracted at the request of the Editors-in-Chief.The article is a duplicate of a paper that has already been published i…
Quantitative Identification of High-Risk Tricuspid Regurgitation by Cardiac Magnetic Resonance
Circulation, Ahead of Print. BACKGROUND:The role of cardiac magnetic resonance (CMR) quantification of tricuspid regurgitation (TR) to identify high-risk patients with TR remains poorly defined. The aim of this study was to assess the prognostic relevance of TR quantification and of its consequence…
N-Palmitoyl Glutamine Is a Candidate Mediator of Cardiorespiratory Fitness
Circulation, Ahead of Print. BACKGROUND:Cardiorespiratory fitness is an integrative measure of cardiometabolic health and predictor of survival, yet little is known about its molecular underpinnings. Small molecule metabolites and lipids are increasingly recognized as exercise-stimulated signaling …
Polmonite: sintomi, cause, diagnosi e trattamento
Polmonite – La polmonite è un’infezione polmonare che può avere cause batteriche, virali o fungine e che può variare da forme lievi a gravi, in base al paziente e all’agente causale. È fondamentale riconoscere tempestivamente i sintomi e rivolgersi a un medico per una diagnosi e un trattament…
Gli italiani e i farmaci: quasi due pillole a testa, boom di anti obesità e psicofarmaci tra i bimbi
Nel 2024 in Italia sono state consumate 1.895 dosi di medicinali ogni 1000 abitanti al giorno, ovvero ogni cittadino, inclusi i bambini, ha assunto circa 1,9 dosi di farmaco. Il…
ETV5-S100A9 feed-forward loop connecting HCC and MDSCs to shape the immunosuppressive tumour microenvironment
Hepatocellular carcinoma (HCC), the most common form of primary liver cancer, is a leading cause of cancer-related deaths worldwide, accounting for approximately 800 000 deaths annually. Treatment options for unresectable, advanced-stage HCC are very limited. For decades, tyrosine kinase inhibitors…
Statin use association with all-cause mortality and liver-related outcomes: are the benefits true?
Zhou and colleagues published an observational study on the beneficial effects of statin use in steatotic liver disease.1 Using a large, multicentre database, the author reported that statin use in patients with metabolic-associated steatotic liver disease (MASLD) at 3-year median follow-up was ass…
