Anatomic versus reverse total shoulder replacement for patients with osteoarthritis and intact rotator cuff: the RAPSODI-UK randomised controlled trial protocol
Introduction
Shoulder osteoarthritis most commonly affects older adults, causing pain, reduced function and quality of life. Total shoulder replacements (TSRs) are indicated once other non-surgical options no longer provide adequate pain relief. Two main types of TSRs are widely used: anatomic TSR …
Impact of COVID-19 on the detection of tuberculosis in Guangdong, China based on the autoregressive integrated moving average model: a time-series study
Objective
China has continued to improve tuberculosis (TB) control in the past decade; however, the sudden outbreak of COVID-19 hindered this progress. As a province with a large population and frequent international exchanges, Guangdong has been seriously affected by COVID-19. This study aimed to …
Studying COVID-19 transmission in US state prisons using an agent-based modelling approach: a simulation study
Objectives
We aim to use an agent-based model to accurately predict the spread of COVID-19 within multiple US state prisons.
Design
We developed a semistochastic transmission model of COVID-19.
Setting
Five regional state-owned prisons within North Carolina.
Participants
Several thousand incarcerat…
Participants experiences with the Delphi method: an online evaluation of a three-round Delphi across German-speaking countries
Objectives
This study evaluates how participants experienced and assessed a three-round Delphi study on the terminology of developmental language disorders in childhood. It compares participants who completed all rounds (completers) with those who withdrew early (dropouts) and aims to derive method…
How can midwives in Germany be supported in advising on early childhood allergy prevention in a health literacy-responsive way? Protocol for a mixed-methods study to co-design and evaluate an educational intervention following the Medical Research Council framework
Introduction
Health literacy (HL) is essential for making informed health-related decisions, for example enabling parents to reduce their child’s allergy risk. Health literacy does not, however, rely solely on an individual’s capacities, but is strongly influenced by external factors. Midwives prov…
La classifica dei migliori ospedali italiani secondo Agenas
Notizie dalla SanitàAGENAS ha pubblicato nuova edizione del Programma Nazionale Esiti (PNE) 2025, basata sui dati relativi al 2024. Il PNE...
Efficacy and moderators of cognitive behavioural therapy versus interpersonal psychotherapy for adult depression: study protocol of a systematic review and individual participant data meta-analysis
Introduction
Cognitive behavioural therapy (CBT) and interpersonal psychotherapy (IPT) are both efficacious treatments for depression, but it is less clear how both compare on outcome domains other than depression and in the longer term. Moreover, it is unclear which of these two psychotherapies wo…
Study protocol for optimising antipsychotic prescribing among hospitalised patients in the acute care setting in Scotland: a national retrospective cohort study
Introduction
Prescribing high-dose antipsychotics is typically reserved for individuals with treatment-resistant severe mental illnesses, such as schizophrenia, bipolar disorder and psychotic depression. It carries an increased risk of adverse drug effects, necessitating regular monitoring. Non-men…
Self-management measurement instruments specific to individuals with cardiovascular diseases: a systematic review protocol using COSMIN methodology
Introduction
Cardiovascular diseases (CVDs) are the leading cause of death worldwide, making the development of self-management strategies crucial for preventing complications and improving clinical outcomes. This process involves symptom monitoring, treatment adherence, emotional management and a …
Decision-making experience of elderly patients for joint replacement surgery in China: a qualitative study
Objectives
To gain an in-depth understanding of the experience of elderly joint replacement patients in making surgical decisions and to identify the needs of patients in the decision-making process.
Design
A qualitative study, semistructured interviews were used and analysed by Colaizzi’s seven-st…
Exploring the links between NITAGs and academic institutions: a landscape analysis protocol
Introduction
National Immunization Technical Advisory Groups (NITAGs) are multidisciplinary groups of national experts who provide independent advice to policy makers on issues related to immunisation and vaccines, based on evidence and the national context. On the other hand, academic institutions…
Priorities of the US Food and Drug Administration—Reply
In Reply We appreciate the Letter from Dr Krommes about our Viewpoint. However, she and Doctors for America are misinformed. No scientific reviewers were let go as part of the reduction in force at the FDA, and our ability to provide timely, accurate reviews is uncompromised. Doctors for America is…
Hidden Pictures
Look, she says, picking a mauve-bellied leaf off a vine. How about the ivy bending around the window? She takes any aid the July morning offers. Or the pink drooping peonies? What about the woolly clouds filling up with water to fall out of the sky? She roll calls the schoolroom of today’s summer, …
Why Medical Economics?
Recent papers by Dr. R. B. Robins, Vice President, American Medical Association, have provoked considerable comment on the questions What is medical economics? What does it mean? The answers are important to the general population and particularly to the medical profession. They are important becau…
A Review of Diverticulitis
To the Editor In the recent Review on colonic diverticulitis by Dr Brown and colleagues, the description of the mechanical pathophysiology of sigmoid diverticula, and specifically the supposed role of the Laplace law, deserves a comment. The law attributed to Pierre-Simon de Laplace (1749-1827) des…
A Review of Diverticulitis—Reply
In Reply We thank Dr Ceelen for his Letter in response to our Review of diverticulitis. As clearly stated in our Review, the pathophysiology of diverticular disease is incompletely understood and indeed multifactorial. The principles of the law of Laplace (P = T/R) for a cylindrical structure provi…
