Medications for Opioid Use Disorder in County Jails — Outcomes after Release
New England Journal of Medicine, Volume 393, Issue 21, Page 2175-2176, November 27, 2025.
Incidence and Mortality of Chronic Subdural Hematomas: A Population-Based Study
Stroke, Ahead of Print. BACKGROUND:Despite a rising public health burden, there have been few population-based studies of chronic subdural hematomas (cSDH) in the United States. We provide the first estimates of cSDH incidence and mortality in a large, representative U.S. population.METHODS:In a re…
Critical Analysis of “Remodeling the Colon With Ileal Properties to Treat Short Bowel Syndrome”
We commend Liu et al1 for their innovative study demonstrating special adenine and thymine–rich sequence-binding protein 2 (SATB2) depletion as a potential therapy for short bowel syndrome (SBS) by inducing ileal-like properties in the colon. Although the findings are promising, several methodologi…
How to Identify Neonates Needing Morphine for Opioid Withdrawal
Among monitored neonates, maternal opioid history proved most accurate for identifying infants who required treatment for withdrawal.
ETV5-S100A9 feed-forward loop connecting HCC and MDSCs to shape the immunosuppressive tumour microenvironment
Hepatocellular carcinoma (HCC), the most common form of primary liver cancer, is a leading cause of cancer-related deaths worldwide, accounting for approximately 800 000 deaths annually. Treatment options for unresectable, advanced-stage HCC are very limited. For decades, tyrosine kinase inhibitors…
Intrahepatic donor microbiota-based metataxonomic signature detected in organ preservation solution enables prediction of short-term liver transplant outcomes
Background
Liver transplantation (LT) remains hampered by post-transplant complications. While gut microbiota dysbiosis has been linked to transplant outcomes, the role of the intrahepatic graft’s native microbiota remains unexplored.
Objective
To characterise the microbial profile detected in orga…
Short-Term Extreme Temperatures, Temperature Fluctuations, and the Risk of Aneurysmal Subarachnoid Hemorrhage: A Nationwide Case-Crossover Study
Stroke, Ahead of Print. BACKGROUND:Previous studies have shown inconsistent links between seasonal variation or ambient temperature and aneurysmal subarachnoid hemorrhage (aSAH) onset. Furthermore, the impact of short-term temperature fluctuations on aSAH remains unclear. This study aims to quantif…
Lifesaving Medicines for Addiction Are Underused by Clinicians
Naloxone was offered to less than a third of patients with opioid use disorder seeking care in EDs.
Targeting the CCL2/CCR2 Axis in HIV-1 Infection and Ischemic Stroke
Stroke, Ahead of Print. HIV-associated comorbidities, including cardiovascular and cerebrovascular events, are frequent diseases in people living with HIV. Notably, the prevalence of ischemic stroke is 3× higher in people living with HIV than in noninfected individuals, making it one of the most si…
High-Voltage Focal Pulsed Field Ablation to Treat Scar-Related Ventricular Tachycardia: The First-in-Human VCAS Trial
Circulation, Ahead of Print. Background: Unlike the tremendous progress made in atrial fibrillation ablation, the greatest unmet clinical need is for innovative ablation treatments for scar-related ventricular tachycardia (VT) – particularly given the thick, often fibrotic tissue characteristic of …
Collaborative Care for Opioid Use Disorder in Primary Care
This cluster randomized clinical trial investigates if collaborative care for opioid use disorder and co-occurring mental health symptoms is superior to collaborative care for co-occurring mental health symptoms alone.
Does Opioid-Induced Dysphagia Respond to Stopping Opioid Use?
In an observational study, symptoms improved or resolved in most patients who were able to discontinue opioid use.
Putting the best foot forward: rethinking the paradigms in ASUC
Acute severe ulcerative colitis (ASUC) remains one of the challenging presentations in inflammatory bowel disease (IBD) where progress on therapeutic approaches has been limited since 1955 when corticosteroids revolutionised care 1 to reduce the mortality associated with ASUC. Despite the advent of…
Positive Emotion Dysregulation in Opioid Use Disorder and Normalization by Mindfulness-Oriented Recovery Enhancement
This study tests whether opioid use disorder (OUD) is associated with attenuated positive emotion regulation and whether such positive emotion dysregulation may be treated by mindfulness-based intervention.
Group Omitted From Article Byline
In the Original Investigation titled “Optimizing Pemphigus Management With Rituximab and Short-Term Relapse Predictors,” published online on February 5, 2025, and in the April 2025 issue, the author byline omitted the MALIBUL group. The article byline was corrected online.
Global prevalence of ultra-short coeliac disease (USCD): the first systematic review and meta-analysis
We reviewed the recent cohort study by Raju et al1 on ultra-short coeliac disease (USCD), the first multicentre international study assessing the characteristics of this new entity and comparing them to classic coeliac disease. The study revealed findings that may necessitate a re-evaluation of the…
