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Gestione farmacologica degli adulti con dislipidemia: linee guida
Questa linea guida pubblicata dall’American Association of Clinical Endocrinology, è […]
Arte-terapia per i bimbi con cancro all'associazione Peter Pan
L’organizzazione accoglie a Roma chi viene da fuori per le cure
Alzheimer, un farmaco sperimentale ripristina la memoria e le altre funzioni cognitive
Un nuovo farmaco sperimentale, GL-II-73, sviluppato dal Centre for Addiction and Mental […]
Iss, i legumi alleati di salute e ambiente ma ancora poco utilizzati
Il 10 la Giornata mondiale. Riducono il rischio di cancro e malattie
Cancro ovarico: Standard di qualità
Nice ha provveduto ad aggiornare e a sostituire la versione […]
Examining the relationship between incidence and mortality for commonly diagnosed cancers in the USA: an observational study using population-based SEER database
Objective
Incidence and mortality are fundamental epidemiologic measures of cancer burden, yet few studies have examined individual cancers to determine how these measures correlate across place. We assessed the relationship between incidence and mortality for commonly diagnosed cancers in the USA.
Design
Population-based observational study of US counties.
Setting and participants
The Surveillance, Epidemiology and End Results (SEER) database was used to obtain incidence (2000–2016) and mortality (2002–2018) data for the 12 most commonly diagnosed non-haematologic cancers.
Outcome measures
County-level correlation between cancer incidence and mortality. Cancers were grouped into terciles based on the population-weighted correlation coefficient (r). We also examined the 10 year risk of death, both from the diagnosed cancer and other causes.
Results
County-level incidence and mortality were strongly correlated in some cancers, yet uncorrelated in others. Cancers in the high-correlation tercile (r range: 0.96 to 0.78) included lung, stomach, liver and pancreas. For patients with these cancers, the risk of death from the diagnosed cancer was >4-times the risk of death from other causes. The moderate-correlation tercile (r: 0.75 to 0.58) included cancers of the colon, bladder, kidney and uterus. There was little or no relationship between incidence and mortality for cancers in the low-correlation tercile (r: 0.33 to –0.10): melanoma, prostate, breast and thyroid. The risk of death from the diagnosed cancer for these patients was either lower or no different than their risk of death from other causes.
Conclusions
For some cancers in the USA, the fundamental epidemiologic measure of disease frequency—incidence—now has little relationship with cancer death (mortality). Low correlations are most likely explained by differences in diagnostic practice leading to variable amounts of cancer overdiagnosis between different US counties.
Unravelling a Case of Fatty Pancreas in a Child
Farmaci contraffatti, 286 siti oscurati e 23 arresti
Sequestro medicinali e sostanze dopanti per oltre 2 mln di euro
UniBa studia intelligenza artificiale applicata a ricerca cancro
E’ partner del progetto ‘European cancer imaging – Eucaim’
Camminare molto e velocemente riduce il rischio di demenza
Indossare uno smartwatch può aiutare a tenere a bada il rischio
Mercato farmaci in farmacia, +0,6% in volume e +2,6% in valore
Tachipirina resta medicinale più venduto nonostante lieve calo
Giornata contro il cancro: 1.500 nuovi pazienti nel 2024
Ast Pesaro-Urbino presenta i numeri del territorio
Campitiello (Ministero Salute), 'accesso più equo alle terapie anti cancro'
‘Gli strumenti ci sono ma bisogna applicarli’
Bianca Balti, 'il cancro mi ha fatto amare molto di più la vita'
Lungo post della modella che sarà sul palco di Sanremo
Nuove linee guida ACP sulla prevenzione dell’emicrania
L’American College of Physicians (ACP) ha sviluppato nuove raccomandazioni per […]