Abstract WP105: Outcomes From the 1st 100 Stroke Survivors Served by a Novel Tech-Enabled Post-Acute Clinical Service

Stroke, Volume 55, Issue Suppl_1, Page AWP105-AWP105, February 1, 2024. Introduction:This study evaluates the outcomes of a survivor-centric, navigator-driven, technology-enabled platform supporting survivors (SS) and care partners(CP) in post-stroke recovery. At current enrollment rates, the abstract will be updated to include 100 program participants and a propensity-matched analysis of readmission rates vs. a Medicare FFS claims set for appropriately matched subjects.Methods:An app-based, virtual care model was used to impact survivor quality of life and improve outcomes for stroke survivors. This mixed methods study utilizes focus group feedback, survey, app usage and patient-reported outcomes data. Participants (n=50) were facilitated by a clinical navigator (OT or LCSW). Clinicians worked through phone, messaging, and video calls with the SS/CP who had shared access within the app, with separate profiles. The average duration of participation was 12 weeks but tailored to individual needs based on post-stroke impairments, social determinants, health literacy, risk factors and lifestyle management, mental health, and other resource needs. The average participant had 10 Navigator touchpoints totaling 8 hours over the duration of the program.Results:Clinician-assessed mRS scores were captured at 90 days following hospital discharge for 96% of participants. Significant functional improvement was seen, with 84% achieving mRS scores of 0-2 at 90 days, compared to 60% of participants at the time of enrollment. The 30- and 90-day all-cause readmission rates for survivors were 5% and 10%, respectively, superior to recent publications reporting 30-day unplanned readmission rates after stroke ranging from 8.7%-12.5%, and 90-day readmissions ranging from 18.9% to 20.7%.Conclusion:These preliminary outcomes indicate that a tech-enabled healthcare services program can engage and impact the outcomes of individuals and care partners during stroke recovery.

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Febbraio 2024

Abstract 100: Impact of Dissection Location on Subsequent Stroke Risk: A Nationwide Analysis

Stroke, Volume 55, Issue Suppl_1, Page A100-A100, February 1, 2024. Introduction:Cervical artery dissection (CAD) is a frequent cause of acute ischemic stroke (AIS) in young adults. We conducted a nationwide study to investigate potential predictors for subsequent AIS following CAD.Method:Adult patients diagnosed with non-traumatic CAD, and without any previous or concurrent stroke (2016-2020), were identified from the Nationwide Readmission Database using validated and standard ICD-10 CM codes. Significant demographic and clinical factors associated with 90-day AIS risk were identified through weighted survey univariate logistic regression followed by a multivariate Cox regression model.Result:Among 13,905 CAD patients (mean age 54.6±0.2, 54.8% female), 215 (1.5%) had subsequent AIS within 90 days of discharge with the median stroke occurrence on day 8. Patients with AIS were significantly older (58.3±1.3 vs. 54.5±0.2,P=0.026), and more commonly had vertebral artery dissection (51.6% vs. 41.0%,P=0.046), and coronary artery disease (24.7% vs. 15.6%,P=0.019). After including all these significant variables, the vertebral artery location of the dissection emerged as the sole significant predictor of subsequent AIS (adjusted HR 1.64, 95% CI 1.07-2.50,P=0.022). A Kaplan-Meier curve validated these findings, showing a higher AIS risk with vertebral versus carotid artery dissections (Figure). Notably, other risk factors such as hyperlipidemia and hypertension lacked significant association with AIS.Conclusion:Our study identifies vertebral artery dissection as a significant risk factor for 90-day AIS occurrence post CAD. This highlights the need for research into tailored management strategies for these patients to reduce stroke risk.

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Febbraio 2024