A Tale of 2 Palliative Care Trials

At first glance, the 2 palliative care trials in this issue of JAMA may seem a study in contrasts. One was an outpatient intervention, the other inpatient. One included 306 participants, the other 24 065. One was an efficacy study, the other a pragmatic effectiveness study. One of the interventions added resources to expand access to palliative care, the other tried to expand access to palliative care with no additional resources. In one study the primary outcome was quality of life (QOL), in the other length of stay (LOS). In one study the primary outcome was positive, in the other it was negative.

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Gennaio 2024

Longitudinal symptom profile of palliative care patients receiving a nurse-led end-of-life (PEACH) programme to support preference to die at home

Objectives
Tailored models of home-based palliative care aimed to support death at home, should also ensure optimal symptom control. This study aimed to explore symptom occurrence and distress over time in Palliative Extended And Care at Home (PEACH) model of care recipients.

Design
This was a prospective cohort study.

Setting and participants
Participants were consecutive recipients of the PEACH rapid response nurse-led model of care in metropolitan Sydney (December 2013–January 2017) who were in the last weeks of life with a terminal or deteriorating phase of illness and had a preference to be cared or die at home.

Outcome measures
Deidentified data including sociodemographic and clinical characteristics, and symptom distress scores (Symptom Assessment Score) were collected at each clinical visit. Descriptive statistics and forward selection logistic regression analysis were used to explore influence of symptom distress levels on mode of separation ((1) died at home while still receiving a PEACH package, (2) admitted to a hospital or an inpatient palliative care unit or (3) discharged from the package (alive and no longer requiring PEACH)) across four symptom distress level categories.

Results
1754 consecutive clients received a PEACH package (mean age 70 years, 55% male). 75.7% (n=1327) had a home death, 13.5% (n=237) were admitted and 10.8% (n=190) were still alive and residing at home when the package ceased. Mean symptom distress scores improved from baseline to final scores in the three groups (p

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Gennaio 2024