Risultati per: La gestione della costipazione indotta dagli oppioidi: il paradigma della qualità delle cure

Domenica dal Villaggio della Salute al via le ‘gare’ di 5 e 2 km

New England Journal of Medicine, Ahead of Print.

Giorlandino (Sidip), per il picco endocrino che avviene in Primavera

‘Ddl Calderoli legittimerà normativamente le disuguaglianze’

Si sono aperti i lavori del tavolo tecnico straordinario riguardante criticità emergenti dall’attuazione dei Regolamenti sull’Assistenza Ospedaliera e Territoriale, SNAMI, unico sindacato della medicina generale presente, è stato rappresentato da Simona Autunnali, tesoriere nazionale Snami

Chronic HBV infection, with hepatic inflammation and viral genome persistence in the hepatocytes either in the form of cccDNA or partially integrated into the host nucleus, is one of the major causes of liver cirrhosis and hepatocellular carcinoma.1 Available therapies for chronic hepatitis B (CHB) include long-term administration of nucleos(t)ide analogues or a finite treatment with polyethylene-glycol (PEG)–interferon alpha (IFN-α) that rarely allow reaching a functional cure, defined as loss of Hepatitis B surface antigen (HBsAg) and undetectable HBV DNA in the serum.1 Thus, a major effort is currently devoted to studies aimed at finding new effective therapies. Different factors contribute to viral persistence. HBV can elude the host immune response, being poorly detected by the innate system and inducing variable degrees of dysfunction of the adaptive immune response up to T-cell and B-cell exhaustion in chronic infection. Moreover, the liver represents a peculiar tolerogenic…