Risultati per: Chirurgia o non chirurgia per la sciatica

Lo dice uno studio Usa. Sarà tra temi congresso mondiale Ifso

Specialisti Beauregard parteciperanno a interventi in Piemonte

Al Policlinico di Modena, i due interventi urgenti

Al Policlinico di Modena, i due interventi urgenti

Effettuate cinque piccole incisioni per via laparoscopica

Discectomies for sciatica, a condition often caused by a herniated disk, might be better than nonsurgical treatments or epidural steroid injections for reducing leg pain and disability in some patients, although the improvements declined over time to a negligible benefit after 12 months. The findings from the analysis of 24 randomized clinical trials were supported by very low- and low-certainty evidence.

Interventi saranno finanziati dal governo nel Mato Grosso do Sul

But low-quality evidence shows benefits decline over time.

Viene affidata la scuola di riferimento nazionale

Introduction
Sciatica is a common condition and is associated with higher levels of pain, disability, poorer quality of life, and increased use of health resources compared with low back pain alone. Although many patients recover, a third develop persistent sciatica symptoms. It remains unclear, why some patients develop persistent sciatica as none of the traditionally considered clinical parameters (eg, symptom severity, routine MRI) are consistent prognostic factors.
The FORECAST study (factors predicting the transition from acute to persistent pain in people with ‘sciatica’) will take a different approach by exploring mechanism-based subgroups in patients with sciatica and investigate whether a mechanism-based approach can identify factors that predict pain persistence in patients with sciatica.

Methods and analysis
We will perform a prospective longitudinal cohort study including 180 people with acute/subacute sciatica. N=168 healthy participants will provide normative data. A detailed set of variables will be assessed within 3 months after sciatica onset. This will include self-reported sensory and psychosocial profiles, quantitative sensory testing, blood inflammatory markers and advanced neuroimaging. We will determine outcome with the Sciatica Bothersomeness Index and a Numerical Pain Rating Scale for leg pain severity at 3 and 12 months.
We will use principal component analysis followed by clustering methods to identify subgroups. Univariate associations and machine learning methods optimised for high dimensional small data sets will be used to identify the most powerful predictors and model selection/accuracy.
The results will provide crucial information about the pathophysiological drivers of sciatica symptoms and may identify prognostic factors of pain persistence.

Ethics and dissemination
The FORECAST study has received ethical approval (South Central Oxford C, 18/SC/0263). The dissemination strategy will be guided by our patient and public engagement activities and will include peer-reviewed publications, conference presentations, social media and podcasts.

Trial registration number
ISRCTN18170726; Pre-results.

Investimento da 4 milioni di euro per ampliare la dotazione

Momento di cooperazione scientifica con l’Università di Padova

Momento di cooperazione scientifica con l’Università di Padova

Momento di cooperazione scientifica con l’Università di Padova