Risultati per: Report aggiornato sulla qualità dell’aria in Europa (2015)

Stroke, Volume 53, Issue Suppl_1, Page AWP27-AWP27, February 1, 2022. Introduction:Recent studies have shown patients with coronavirus disease 2019 (COVID-19) develop significant coagulopathy with thromboembolic complications including ischemic stroke. However, data are sparse regarding the clinical characteristics, stroke mechanism, and patient outcomes.Methods:We conducted a retrospective cohort study of consecutive patients with ischemic stroke who were hospitalized between March 2020 and June 2021, within at a Regional Medical Center serving three large counties in South Carolina. We further investigated clinical and demographic characteristics, stroke severity as measured by the National Institutes of Health Stroke Scale (NIHSS), and stroke subtype as measured by the TOAST (Trial of ORG 10172 in Acute Stroke Treatment) criteria among patients with COVID-19 who also suffered from an acute ischemic stroke.Results:During the study period, out of 1087 hospitalized patients with a diagnosis of COVID-19 infection, 18 patients (1.6%) had an imaging-proven ischemic stroke. Of these 18 patients, 10 (56%) were men, 16 were African-Americans (89%), 2 (11.1%) patients were

Stroke, Volume 53, Issue Suppl_1, Page ATP15-ATP15, February 1, 2022. Introduction:Stroke increases the risk of cognitive and motor impairment long after the subacute recovery period. Clinicians often rely on patients to self-report symptoms, though this may not always align with objective findings. The aim of this study was to determine the associations between self-report and objective methods of evaluation when examining cognitive and motor functioning in stroke survivors.Methods:Seventy ischemic stroke participants over age 45 completed the Hopkins Verbal Learning Test-Revised (HVLT) and the Finger Tapping Test (FTT) 5-13 months post-stroke as part of the StrokeCog study. Performance of at least one standard deviation below the normative mean was considered abnormal. Self-report ratings in memory and thinking, hand function, and depression were assessed with the Stroke Impact Scale (SIS) as well as fatigue (FACIT) and stroke severity (NIHSS). Logistic regression was used to assess associations with HVLT and FTT performance as dependent factors.Results:Thirty-nine percent of participants demonstrated abnormal memory performance on the HVLT. The normal and abnormal memory groups did not differ in self-reported memory (p = 0.242) or depression (p = 0.232). A trend towards less stroke severity among patients with normal (median (IQR) NIHSS 2 (1-8)) vs. impaired memory exists (NIHSS 6 (2-12.5); p = 0.08). Less fatigue (OR (95% CI) 1.05 [1.001-1.11]) and female sex (OR 3.80 [1.09-13.21]) were independently associated with normal memory. Fifty-two percent of participants demonstrated abnormal motor performance on the FTT. The normal and abnormal motor groups did not differ in self-reported hand function (p = 0.285). Male sex (OR 19.6 [3.8-100]) and lower depression (OR 1.12 [1.05 – 1.20]) were independently associated with normal motor function.Conclusion:Self-report did not align with objective assessments of memory and fine motor functioning in stroke survivors. Fatigue and male sex were associated with memory impairment while depression and female sex were associated with motor impairment. This highlights the role of fatigue and depression in long-term stroke outcomes and the importance of using both objective and subjective methods when evaluating cognitive and motor impairment.

Comunicato del 01/09/2021 n°56