Ascierto, +25% di sopravvivenza in forme malattia avanzate
Risultati per: Valutazione e gestione del Melanoma
Questo è quello che abbiamo trovato per te
Melanoma, occhio alla tintarella sulla neve. Solo 1 su 10 si protegge
Ascierto, ‘dai raggi solari ci si deve difendere anche in inverno’
Melanoma, terapia con virus modificato per i casi difficili
Efficace nel 30% dei pazienti che non risponde alle altre cure
Linea guida sulla diagnosi, monitoraggio e gestione dell’asma
PD-L1 Expression for Tailoring Treatment in Advanced Melanoma—It Is Never That Easy
To the Editor We read with great interest the comments by Donia and Prasad suggesting that for patients with tumors exhibiting positive staining (≥1%) for programmed cell death ligand 1 (PD-L1), nivolumab monotherapy offers maximal benefit while cautioning against the necessity of the combination therapy due to toxic effects and cost. However, we wish to address certain points and express our reservations regarding this stance.
Racial and Ethnic Differences in the Risk of Second Primary Melanoma
This cohort study assesses the incidence of a second melanoma diagnosis after initial diagnosis among racial and ethnic minority populations.
PD-L1 Expression for Tailoring Treatment in Advanced Melanoma—It Is Never That Easy—Reply
In Reply We appreciate the thoughtful comments to this Viewpoint by Karahan et al that emphasize the importance of considering additional predictive parameters when determining immunotherapy treatment strategies for patients with advanced melanoma. In patients with treatment-naive unresectable or metastatic melanoma and no central nervous system metastases, various clinical and molecular biomarkers, including programmed cell death ligand 1 (PD-L1) status (1% cut-off), liver metastases, BRAF mutational status, and the number of involved metastatic organs may help guide the shared decision-making process for dual checkpoint inhibition with ipilimumab plus nivolumab vs anti–programmed cell death 1 (PD-1) monotherapy. In addition, acknowledging the challenges in precisely defining this population in clinical trials and clinical studies, patients with rapidly progressing and/or symptomatic disease, very high tumor burden, or disease localization in organs at high risk (eg, close to critical anatomic structures like the spinal cord or upper airways) might obtain superior benefit from combination therapy with ipilimumab plus nivolumab due to the fast kinetics of response. To our knowledge, no defined biomarkers, other than PD-L1 at the 1% cut-off, exist for guiding the choice between the combination of relatlimab plus nivolumab and anti-PD-1 monotherapy.
Raccomandazioni EULAR per la gestione dell’artrite reumatoide con farmaci antireumatici sintetici e biologici modificanti la malattia
Linee guida melanoma
Diagnosi e gestione della Leucemia Mieloide Cronica (LMC) negli adulti
Linee guida EAN sulla gestione della sclerosi laterale amiotrofica (SLA)
Marsh Italia, gestione del rischio per una sanità più sicura
Araldi, ‘con MedMal Report identifichiamo aree più a rischio’