Risultati per: Sindrome da immunodeficienza umana - AIDS

Da ricercatori italiani e americani. Utile anche contro i tumori

But hearing aids imparted no cognitive benefit after 3 years in lower-risk patients.

Il fenomeno di Raynaud colpisce fino al 5% della popolazione

Objectives
To estimate the own-price, cross-price and income elasticities for carbonated soft drinks (CSDs), malt drinks, chocolate powder, sachet water and sugar in Nigeria. These elasticities can be used to estimate the potential demand response to the recently-introduced sugar tax in Nigeria.

Setting
The study uses household data from the 2018/2019 Nigeria Living Standards Survey (NLSS).

Participants
The NLSS is a national household survey. 21 114 households were included in the final sample for this analysis.

Primary and secondary outcomes
We used Deaton’s almost ideal demand system, which controls for the goods’ quality, to estimate the effect of price and income changes on the demand for CSDs, chocolate powder, malt drinks, sachet water and sugar.

Results
We found that the own-price elasticity (ordered from most to least price-responsive) was –0.99 (p

Objective
This study assessed the magnitude of risky sexual practices and associated factors among adult people living with HIV (PLHIV) attending antiretroviral clinics in public hospitals in Kembata Tembaro Zone, southern Ethiopia.

Design
A cross-sectional study was conducted.

Setting
A hospital-based study was conducted among adult PLHIV in the Kambata Tambaro Zone, southern Ethiopia.

Participants
300 men and women aged 15 years and older who had been receiving HIV/AIDS care and support in four public hospitals participated in this study.

Study outcome
Risky sexual practice was the study outcome. It was defined based on responses to four items: multiple sexual partnerships, casual sex, consistent condom use and sex under the influence of alcohol. Risky sexual practice was defined based on a ‘yes’ response to any of the four items.

Results
Of the adult PLHIV who were sexually active in the 6 months preceding the survey, 75.7% (95% CI: 70.5% to 80.2%) engaged in at least one risky sexual practice, with 3.3% (95% CI: 1.8% to 6.1%) engaged in three or more. A positive attitude towards condom use and being on antiretroviral therapy for over 10 years were correlated with low odds of risky sexual practices. There was a higher likelihood of risky sexual behaviour among those who kept their HIV status secret and did not bring up using a condom before sexual contact. Whereas, those with a positive attitude towards condom use had a reduced risk of engaging in risky sexual practices.

Conclusion
A considerable proportion of adult PLHIV engage in risky sexual practices. Efforts directed at removing barriers to disclosing HIV status to partners and promoting condom use discussion among sexual partners could reduce the burden of risky sexual practices and the onward transmission of HIV.

Soffre di una malattia rarissima che la rendeva sterile. il parto a Torino

Sie, malattia della ‘faccia a luna piena’ tra le patologie rare

Cura già possibile privatamente ma con molte difficoltà e costi

Iss, fornirà consulenza dalla 9 alle 19 da lunedì al venerdì

Ok da Fda, molecola allevia di molto sintomi della malattia rara

La cura inaspettata, con Zaccheddu. I 40 anni di storia dell’Hiv

New England Journal of Medicine, Ahead of Print.

Colpisce circa 600 persone in Italia, porta a dialisi o morte

E’ la Esofagite eosinofila, malattia poco conosciuta. Attenzione ai sintomi

Objectives
Non-adherence to antipsychotics is the greatest obstacle to treating schizophrenia. We assessed the economic and clinical impacts of adherence to antipsychotics among people living with HIV/AIDS (PLWH) and schizophrenia in British Columbia, Canada.

Design and setting
A population-based cohort study in British Columbia, Canada.

Methods
Eligible PLWH were enrolled in the Seek and Treat for Optimal Prevention HIV/AIDS population-based cohort during 2001–2016, diagnosed with schizophrenia, on antipsychotics for ≥1 day, and followed for ≥1 year from schizophrenia diagnosis date or 1 January 2001, whichever occurred last.

Primary and secondary outcome measures
A two-part model assessed the marginal effect of adherence on healthcare costs (in 2016 Canadian dollar), while logistic regression examined the effect on virological failure, and generalised linear mixed models examined the effect on hospital readmissions within 30 days and length of hospital stay.

Results
Among 726 PLWH with schizophrenia, ≥80% adherence to antipsychotics increased from 25% (50/198) in 2001 to 41% (225/554) in 2016. In most years, we observed no difference in adherence to antipsychotics among those who used only injectables, only non-injectables, and a combination of both, or among those who have ever consumed typical/first-generation antipsychotics and who consumed only atypical/second-generation antipsychotics. Overall healthcare costs were higher in the non-adherent group ($C2185), driven by the average annual hospitalisation costs ($C5517), particularly among women ($C8806) and people who ever injected drugs (PWID) ($C5985). Non-adherent individuals also experienced higher hospital readmissions (adjusted odds ratio (aOR) 1.48, 95% CI 1.23 to 1.77), and longer hospital stays (adjusted mean ratio 1.23, 95% CI 1.13 to 1.35) in comparison to adherent individuals. We found no difference in virological failure by adherence groups, except when we stratified by gender where the aOR for women was 2.48 (95% CI 1.06 to 5.82).

Conclusions
Our results showed that implementing strategies and interventions to increase antipsychotic adherence, particularly among women and PWID, will be critical in addressing this public health challenge.