Risultati per: Le campagne di screening come strumento di prevenzione oncologica tra dubbi e certezze

Annals of Internal Medicine, Ahead of Print.

Annals of Internal Medicine, Ahead of Print.

Per esami pre natale. Appello dell’immunologo e di Zaccheddu.

Numero uno del Coni presente allo start della Race for the Cure

“La collaborazione con il ministero della salute si consoliderà”

New England Journal of Medicine, Ahead of Print.

Introduction
The management of perinatal depression (PND) is challenging in China. The Thinking Healthy Programme (THP), developed under the core theory of cognitive–behavioural therapy, is an evidence-based approach that is recommended as a psychosocial intervention for managing PND in low/middle-income countries. Sparse evidence has been generated, however, to assess the effectiveness of THP and guide its implementation in China.

Methods and analysis
A hybrid type II effectiveness–implementation study is ongoing in four cities in Anhui Province, China. A comprehensive online platform, Mom’s Good Mood (MGM), has been developed. Perinatal women are screened using the WeChat screening tool (ie, Edinburgh Postnatal Depression Scale embedded as metrics) in clinics. Different intensities of the intervention are delivered through the mobile application for different degrees of depression, according to the stratified care model. The THP WHO treatment manual has been tailored to be the core component of intervention. Guided by the Reach, Effectiveness, Adoption, Implementation and Maintenance framework, process evaluations will be conducted to identify the facilitators and barriers to implementation and to modify the implementation strategy; summative evaluations will be carried out to examine the effectiveness of MGM in the management of PND within the primary healthcare system in China.

Ethics and dissemination
Ethics approval and consent for this programme were obtained from Institutional Review Boards in China: Anhui Medical University, Hefei, People’s Republic of China (20170358). Results will be submitted to relevant conferences and peer-reviewed journals.

Trial registration number
ChiCTR1800016844.

Preventive care for one of the world’s leading infectious disease killers has received a much-needed push forward. In this issue of JAMA, the US Preventive Services Task Force (USPSTF) updates its recommendation to screen asymptomatic adults at increased risk for tuberculosis infection and highlights the critical role of primary care in tuberculosis prevention. The importance of this recommendation, particularly for immigrant communities who bear the disproportionate burden of this disease, cannot be overstated. In the US, more than half of individuals diagnosed with tuberculosis are hospitalized, and almost 1 in 10 will die of the disease. The toll encompassing survival following tuberculosis treatment reveals that 1 in 5 diagnosed with tuberculosis will die within 5 years. These statistics are grim for a preventable and curable disease. The new USPSTF recommendation, rooted in updated evidence, calls for collective action to provide high-quality tuberculosis preventive care for immigrants and other marginalized populations.

This systematic review to support the 2023 US Preventive Services Task Force Recommendation Statement on screening for latent tuberculosis infection in adults summarizes published evidence on the benefits and harms of screening for, and treatment of, tuberculosis in asymptomatic persons 18 years or older.

This JAMA Patient Page describes latent and active tuberculosis and discusses the pros and cons of screening for latent tuberculosis.

This 2023 Recommendation Statement from the US Preventive Services Task Force recommends screening for LTBI in populations at increased risk (B recommendation).

This JAMA Internal Medicine Patient Page describes benefits and harms of cancer screening and how to decide when it may be time to stop routine screening.

Il presidente si è sottoposto questa mattina al test a Trieste

Objective
The primary objective was to quantify psychosocial risk in family caregivers (FCs) of children with medical complexity (CMC) during the COVID-19 pandemic using the Psychosocial Assessment Tool (PAT). The secondary objectives were to compare this finding with the average PAT score of this population before the COVID-19 pandemic and to examine potential clinical predictors of psychosocial risk in FCs of CMC.

Design
Cross-sectional study.

Participants
FCs of CMC were recruited from the Long-Term Ventilation Clinic at The Hospital for Sick Children, Toronto, Ontario, Canada. A total of 91 completed the demographic and PAT questionnaires online from 10 June 2021 through 13 December 2021.

Main outcome measures
Mean PAT scores in FCs were categorised as ‘Universal’ low risk, ‘Targeted’ intermediate risk or ‘Clinical’ high risk. The effect of sociodemographic and clinical variables on overall PAT scores was assessed using multiple linear regression analysis. Comparisons with a previous study were made using Mann-Whitney tests and 2 analysis.

Results
Mean (SD) PAT score was 1.34 (0.69). Thirty-one (34%) caregivers were classified as Universal, 43 (47%) as Targeted and 17 (19%) as Clinical. The mean PAT score (1.34) was significantly higher compared with the mean PAT score (1.17) found prior to the COVID-19 pandemic. Multiple linear regression analysis demonstrated an overall significant model, with the number of hospital admissions since the onset of COVID-19 being the only variable associated with the overall PAT score.

Conclusion
FCs of CMC are experiencing significant psychosocial stress during the COVID-19 pandemic. Timely and effective interventions are warranted to ensure these individuals receive the appropriate support.

Objective
To compare the long-term psychosocial consequences of mammography screening among women with breast cancer, normal results and false-positive results.

Design
A matched cohort study with follow-up of 12–14 years.

Setting
Denmark from 2004 to 2019.

Participants
1170 women who participated in the Danish mammography screening programme in 2004–2005.

Intervention
Mammography screening for women aged 50–69 years.

Outcome measures
We assessed the psychosocial consequences with the Consequences Of Screening–Breast Cancer, a condition-specific questionnaire that is psychometrically validated and encompasses 14 psychosocial dimensions.

Results
Across all 14 psychosocial outcomes, women with false-positive results averagely reported higher psychosocial consequences compared with women with normal findings. Mean differences were statistically insignificant except for the existential values scale: 0.61 (95% CI (0.15 to 1.06), p=0.009). Additionally, women with false-positive results and women diagnosed with breast cancer were affected in a dose–response manner, where women diagnosed with breast cancer were more affected than women with false-positive results.

Conclusion
Our study suggests that a false-positive mammogram is associated with increased psychosocial consequences 12–14 years after the screening. This study adds to the harms of mammography screening. The findings should be used to inform decision-making among the invited women and political and governmental decisions about mammography screening programmes.