Risultati per: Diagnosi, trattamento e follow-up dei pazienti con vescica iperattiva

Aiom lancia una campagna per sensibilizzare malati e caregiver

Aiom lancia una campagna per sensibilizzare malati e caregiver

Objectives
This study aimed to investigate the association between age-specific and sex-specific continuous metabolic syndrome severity score (cMetS-S) and the risk of developing type 2 diabetes mellitus (T2DM). Additionally, the study aimed to assess the added value of cMetS-S in predicting T2DM compared with traditional MetS criteria.

Design
The study used a longitudinal cohort design, following participants for 18 years.

Setting
The research was conducted within the Tehran Lipid and Glucose Study, a community-based study in Tehran, Iran.

Participants
A total of 6957 participants aged 20–60 years were included in the study.

Interventions/exposures
The cMetS-S of each participant was determined using age-specific and sex-specific equations and Cox proportional hazard regression models were used to analyse the association between cMetS-S and T2DM using continuous and quantile approaches.

Primary and secondary outcome measures
The outcome measure was the association between cMetS-S and the development of T2DM during the 18-year follow-up.

Results
A total of 1124 T2DM cases were recorded over 18 years of follow-up. In the fully adjusted model, a 1-SD increase in the cMetS-S was associated with future T2DM (HR 1.72; 95% CI 1.54 to 1.91). Men and women had HRs of 1.65 (95% CI 1.40 to 1.95) and 1.83 (95% CI 1.59 to 2.10) for T2DM per 1-SD increase in cMetS-S, respectively. Higher cMetS-S was associated with increased risk of diabetes in both prediabetic (HR 1.42;95% CI 1.23 to 1.64) and normoglycaemic individuals (HR 2.11;95% CI 1.76 to 2.54); this association was more significant in normoglycaemic individuals. Unlike the traditional-based MetS definitions, the cMetS-S improved diabetes prediction (p

Anderloni (Aigo): “Contano gli stili di vita e diagnosi precoce”

Anderloni (Aigo): “Contano gli stili di vita e diagnosi precoce”

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Circulation, Ahead of Print.