Risultati per: Position paper della French Headache Society sul trattamento dell'emicrania

Circulation, Volume 148, Issue Suppl_1, Page A159-A159, November 6, 2023. Background:While short-term prognosis of cardiac arrest (CA) patients has been extensively studied, less is known regarding the mid- and long-term outcome of survivors.Aims:The aim of the DESAC study was to describe mid- and long-term survival and neurological status of CA survivors, and to assess the influence of pre- and intra-hospital therapeutic strategies on these outcomes.Methods:Between Jul 2015 and Oct 2018, patients over 18 years who were discharged alive from intensive care units in Paris and suburbs (France) after a non-traumatic CA were included and interviewed every 6 months during at least 24 months and up to 48 months in this multicentric study. Factors associated with Cerebral Performance Category (CPC) scale at 24 months were assessed with logistic regression, with CPC 1 or 2 level considered as a favorable neurological outcome. Trajectories of CPC were derived by mixed linear model in survivors with at least 3 evaluations.Results:Out of 593 survivors, 525 had a 24 months follow-up (mean age 57.6 +/-15.3, 79% men). CA occurred in public location in 251/525, with an initial shockable rhythm in 392/525. Prognostic factors independently associated with a favorable neurological outcome at 24 months were initial shockable rhythm (OR= 3.53 (1.65; 7.58)) and previous practice of sport (OR= 3.12 (1.20 ; 8.11)), whereas older age (OR per 10 years= 0.52 (0.40; 0.68)) and previous ischemic cardiomyopathy (OR= 0.34 (0.15 ; 0.77)) were poor prognostic factors. Therapeutic hypothermia or coronary procedures were not related to prognosis. Five trajectories of CPC could be derived among the 514 patients. Overall, 64% remained in CPC1, 13% in CPC2, 11% improved from CPC2 to CPC 12% died either early or lately (Figure 1).Conclusions:In this multicentric and prospective study, practice of sport and shockable rhythm were strongly associated with a favorable neurological recovery at 24 months. Furthermore, two thirds of the survivors remained in CPC 1 over time.

Circulation, Volume 148, Issue Suppl_1, Page A13714-A13714, November 6, 2023. Introduction:Individuals of low socioeconomic position are at greatest risk for incident heart failure (HF). Few data exist, however, regarding factors associated with mortality among individuals with prevalent HF and low socioeconomic position.Methods:The Southern Community Cohort Study (SCCS) is a prospective observational study of 84,797 individuals of predominantly low socioeconomic position enrolled between 2002 to 2009 from 12 states in the southeastern US. Using Cox regression models, we examined demographic, social determinants, and clinical factors associated with 5-year all-cause mortality in a subset of 4,309 black or white adults with prevalent HF receiving Centers for Medicare and Medicaid Services at enrollment. Death was ascertained through linkage with the National Death Index and cohort follow-up.Results:Individuals with prevalent HF at SCCS enrollment were predominantly middle age (mean ~59 years), female (64%), black (70%), low income (75%

Circulation, Volume 148, Issue Suppl_1, Page A220-A220, November 6, 2023. Background:Ventricular fibrillation (VF) or ventricular tachycardia (VT) are the most treatable causes of out-of-hospital cardiac arrest (OHCA). Yet, it remains unknown if defibrillator pad position, placement in the anterior-posterior (AP) or anterior-lateral (AL) positions, impacts patient outcomes in VF/VT OHCA.Aim:Evaluate the association between initial defibrillator pad placement (AP vs. AL) and OHCA outcomes for patients presenting with VF/VT.Methods:This was a prospective observational study of non-traumatic OHCA patients with initial VF/VT on EMS rhythm analysis treated by a single EMS agency in the Portland Cardiac Arrest Epidemiologic Registry (PDX Epistry) from July 1st, 2019 through October 15th, 2022. Our primary outcome was return of spontaneous circulation (ROSC) at any time and secondary outcomes were ROSC at emergency department (ED) arrival, survival to admission, survival to discharge, and functional survival (cerebral perfusion category score of ≤2). We performed t-tests, chi-squared tests, and multivariable logistic regressions adjusting for age, sex, witness status, bystander interventions, arrest location, 911 call to EMS arrival time, and year of arrest.Results:A total of 243 OHCA patients met inclusion criteria and 232 (95.5%) had initial pad positioning documented (133 AP and 99 AL). Patients with AP placement had higher rates of ROSC at any time (72.2% vs. 47.5%, p

Circulation, Volume 148, Issue Suppl_1, Page A13662-A13662, November 6, 2023. Background:Left atrial appendage (LAA) of Asians is generally larger and more complicated than that of non-Asians. Whereas the four classifications from previous reports are widely used in the world, different physicians have different point of views in the real-world practice.Purpose:To identify the relationship between morphological features of LAA and cardioembolic stroke in Japanese patients.Methods:All left atrial appendage closure (LAAC) cases in our institution performed between February 2020 and April 2023 were retrospectively analyzed. The three-dimensional printing of LAA was generated from cardiovascular computed tomography imaging data. The shapes of the LAA were classified into 3 morphological types: (1) The LAA with bi lobe was defined as “Scissors” type; (2) The one with complicated peripheral branches was “Paper” type; (3) The simple one was “Rock” type. We examined the relationship between the risk of cardioembolic stroke and the morphological features of the LAA.Results:The cohort consisted of 93 consecutive patients (age, 75±1 years; male gender, 72%; the size of WATCHMAN device, 29±0 mm). There were 41 (44%) patients who had a history of cardioembolic stroke (27% vs. 41% vs. 58%; Rock vs. Scissors vs. Paper types, p-value = 0.0466). In the multivariate analysis, the Paper type is the potential risk factor of cardioembolic stroke (p-value < 0.01) (Table1.2).Conclusions:The morphological features of LAA by three-dimensional printing was significantly related to cardioembolic stroke in this population. Physicians should pay attention to anticoagulant therapy management and proactively consider LAAC in LAA with complicated peripheral branches.

Annals of Internal Medicine, Ahead of Print.

Annals of Internal Medicine, Ahead of Print.

Stroke, Ahead of Print.

Annals of Internal Medicine, Ahead of Print.

Annals of Internal Medicine, Ahead of Print.

A pochi vengono prescritti i nuovi farmaci che riducono attacchi

A pochi vengono prescritti i nuovi farmaci che riducono attacchi

San Raffaele Roma, Italia prima al mondo per pazienti coinvolti