Decisions to decline breast screening and/or breast cancer treatment based on the potential harms of overdiagnosis and overtreatment: a qualitative study

Objectives
To explore the experiences of women who have made the decision to decline breast screening and/or breast cancer treatment for overdiagnosis/overtreatment reasons after being invited to the National Health Service Breast Screening Programme (NHS BSP).

Design
Qualitative interview study using reflexive thematic analysis.

Setting
Participants were recruited via social media, online forums and word of mouth. Semi-structured interviews were conducted between May 2021 and April 2022.

Participants
20 women aged between 49 and 76 years old who had declined one or more of the following after receiving an invitation to participate in the NHS BSP: (1) screening investigation, that is, mammogram; (2) further investigations, for example, biopsy, ultrasound; (3) treatment, for example, mastectomy, chemotherapy, radiotherapy and (4) any other medical intervention, for example, ongoing medication.

Results
The three main themes were as follows: (1) the perception that the NHS BSP information was biased towards uptake and so constrained choice; (2) taking an active role in decision-making by considering the benefits and harms of the NHS BSP and (3) navigating potential regret for having declined.

Conclusions
In-depth understanding of the potential harms of overdiagnosis and overtreatment influenced the decision to decline for these participants and contributed to their dissatisfactions with the way that information was presented in the invitation to the NHS BSP and the women felt confident in their assessments of the benefits and harms. These findings differ from previous studies, which have suggested that the vast majority lack knowledge and understanding of what overdiagnosis and overtreatment are whereas the participants in this study demonstrated high levels of health literacy. Findings have implications for the way informed choice is considered and constructed in relation to the NHS BSP.

Leggi
Dicembre 2024

Socioeconomic inequality in cervical cancer screening uptake among women in sub-Saharan Africa: a decomposition analysis of Demographic and Health Survey data

Objective
To examine socioeconomic inequalities in the use of cervical cancer screening among women in sub-Saharan Africa.

Design
Secondary data from the Demographic and Health Survey data in sub-Saharan Africa.

Setting
Sub-Saharan Africa.

Participants
Women aged 15–64 years.

Outcome measures
Socioeconomic inequalities in cervical cancer screening uptake and the pooled prevalence of cervical cancer screening.

Results
The pooled prevalence of cervical cancer screening among women in sub-Saharan African countries was 10.51% (95% CI: 7.54% to 13.48%). Cervical cancer screening uptake showed a significant pro-rich distribution of wealth-related inequalities, with a weighted Erreygers normalised concentration index of 0.084 and an SE of 0.003 (p value

Leggi
Dicembre 2024

Can oral cancer screening reduce late-stage diagnosis, treatment delay and mortality? A population-based study in Taiwan

Objective
This study evaluates the effectiveness of Taiwan’s nationwide oral cancer screening programme in reducing late-stage diagnosis, treatment delays and mortality.

Design
A retrospective cohort study was conducted.

Setting
The study utilized Nationally representative datasets, including the Cancer Registry, Oral Mucosal Screening and National Health Insurance databases in Taiwan.

Participants
The study included patients with oral cancer diagnosed between 1 January 2010 and 31 December 2013, with follow-up through 31 December 2018. The final analysis included 16 430 patients.

Intervention
The intervention was Taiwan’s nationwide oral cancer screening programme which provides visual inspection and palpation of the oral mucosa.

Primary outcome measures
The primary outcomes measured were late-stage diagnosis (stages III and IV), treatment delay (time from diagnosis to treatment >30 days) and all-cause mortality.

Results
Oral cancer screening was statistically significantly associated with a reduced likelihood of late-stage diagnosis (adjusted OR (AOR)=0.85, 95% CI 0.80 to 0.91, p

Leggi
Dicembre 2024