Peri-Stenotic Stagnation Associates With Red Blood Cell-Rich Thrombi, Linked to Stroke Recurrence and Lesion Volume
Stroke, Ahead of Print. BACKGROUND:Despite antiplatelet therapy, plaque-induced strokes recur frequently. This recurrence may reflect thrombus heterogeneity driven by peri-stenotic stagnation and red blood cell (RBC) entrapment. The clinical implications of such variations for stroke outcomes remai…
[Articles] Association and post-iliac vein stenting symptom improvement of postural orthostatic tachycardia syndrome and orthostatic intolerance with pelvic venous disorders: two retrospective studies
The high prevalence of PeVD in POTS/OI patients suggests an association between the two diagnoses. In the absence of expert clinical review, screening with US, CT, and MR may not be sufficient to rule out PeVD. Significant improvements were seen in QoL in patients with POTS/OI and PeVD who underwen…
Acute Coronary Syndromes in Premenopausal Women: A Scientific Statement From the American Heart Association
Circulation, Ahead of Print. Premenopausal women presenting with acute coronary syndrome (ACS) are a unique and often underrecognized patient population. Although they are traditionally considered at lower cardiovascular risk than other groups, we have begun to appreciate the potential risk for ACS…
Standard di Cura per il Sovrappeso e l’Obesità
Obesità e SovrappesoSviluppati dal Comitato per la pratica professionale dell’Obesity Association, con il contributo e il supporto di numerose organizzazioni...
Gestione precoce dei pazienti con ictus ischemico acuto: linea guida AHA/ASA
CardiovascolareLe linee guida del 2026 pubblicate dall’American Heart Association/American Stroke Association aggiornano le versioni del 2018 e del...
Linea guida sulla gestione dell’arresto cardiaco in ambito extra e intraospedaliero
CardiovascolareLa Linea Guida italiana sulla gestione dell’arresto cardiaco in ambito extra e intraospedaliero pubblicata da SNLG mira a fornire...
SIGN: linea guida sulla gestione del dolore cronico (parte 1)
Senza categoriaQuesta linea guida si concentra sulla gestione del dolore cronico non maligno (dolore di durata superiore a 12 settimane) negli adulti. Si...
Ipercolesterolemia familiare: linee guida della “National Lipid Association”
CardiovascolareLa National Lipid Association ha aggiornato le linee guida pubblicate nel 2011 sulla diagnosi e gestione della ipercolesterolemia...
Gestione del cancro ovarico epiteliale: linea guida ESMO
Cancro dell'ovaioL’European Society for Medical Oncology ha pubblicato una linea guida sulla gestione del cancro ovarico epiteliale. Si tratta di un...
MOLECULAR AND RESTING-STATE BRAIN CONNECTIVITY LINKS TO STRESS REACTIVITY IN ULCERATIVE COLITIS
Perceived stress has previously been associated with increased flare risk in ulcerative colitis (UC) patients, and we have demonstrated that a psychometrically-based Stress Reactivity (SR) phenotype is associated with increased risk of flares and altered gut microbiome composition in ulcerative col…
Autophagy in Stress-Induced Neuropsychiatric Disorders and Depression
This article discusses how autophagic mechanisms mediate neurobiological and behavioral changes in stress-induced neuropsychiatric disorders and depression.
Oxytocin, Physical Intimacy, Wound Healing, and Stress Responses
This randomized clinical trial examines the effects of repeated intranasal oxytocin administration and a behavioral microintervention on neuroendocrine stress responses and dermatological wound healing.
IMPACT OF BODY MASS INDEX ON EFFICACY AND SAFETY OUTCOMES OF VEDOLIZUMAB IN PATIENTS WITH ULCERATIVE COLITIS: A POST HOC ANALYSIS OF THE VISIBLE 1 CLINICAL TRIAL
The global prevalence of obesity and inflammatory bowel disease (IBD) has increased in recent decades. Body mass index (BMI) is a commonly used surrogate measure of adiposity routinely reported as demographic data in clinical trials. The subcutaneous (SC) formulation of vedolizumab was approved in …
Error in Abstract
In the Original Investigation titled “Intranasal Oxytocin and Physical Intimacy for Dermatological Wound Healing and Neuroendocrine Stress: A Randomized Clinical Trial,” published online November 12, 2025, there was an error in the Results of the Abstract. The value for the association of greater s…
Collaborative Care for Opioid Use Disorders
More than 7.6 million people in the US have opioid use disorder (OUD), and in 2022, there were 81 086 opioid-involved overdose deaths. Medications for OUD (MOUD) reduce overdose risk by 50% yet are prescribed for only 1 in 4 individuals with OUD. Watkins and colleagues report findings from the CLAR…
Collaborative Care for Opioid Use Disorder and Mental Illness
This randomized clinical trial investigates whether collaborative care, tailored for patients with opioid use disorder and co-occurring depression and/or posttraumatic stress disorder, improves outcomes more so than enhanced usual care.
