Search Results for: Melanoma cutaneo

Dal melanoma al tumore del polmone, dal cancro al seno triplo negativo a quello del colon-retto e della vescica: sono sempre più numerosi i tumori per cui la somministrazione dell’immunoterapia neoadiuvante, cioè del trattamento prima dell’intervento chirurgico, mostra evidenze di maggiore efficacia. Questa nuova evoluzione dell’immunoterapia è al centro della seconda edizione di “I.N.N.O.VA.T.E. – International Neoadjuvant Immunotherapy Across Cancers”, al via oggi, e fino a domani, a Napoli.

Dopo aver dimostrato la sua efficacia nel melanoma, il farmaco immunoterapico Daromun, iniettabile direttamente nella massa tumorale, sembra essere promettente anche nel trattamento dei tumori cutanei più diffusi: il carcinoma basocellulare e quello squamocellulare. I risultati preliminari di uno studio di fase II verranno discussi domani a Napoli in occasione della seconda edizione del congresso INNOVATE – International Neoadjuvant Immunotherapy Across Cancers

Melanoma – Melanoma e tumori della pelle in aumento, ma nuove terapie riducono recidive e migliorano la sopravvivenza. Controlli dermatologici ancora troppo scarsi.

Introduction
Dermoscopy has a proved validity in the diagnosis of cutaneous melanoma, which is one of the most aggressive forms of skin cancer. Although some studies have demonstrated a relationship between specific dermoscopic and pathologic melanoma features, there is no solid evidence allowing reliable conclusions. This study will evaluate the evidence regarding this association.

Methods and analysis
Observational studies eligible for our systematic review will enrol adults with histological cutaneous non-volar melanoma diagnosis and with dermoscopy image analysis. We will search the following databases: PubMed, Embase, Web of Science, MEDLINE and Cochrane Library. We will not impose any language or date restrictions. Outcomes of interest include the association of at least one of the melanoma dermoscopy features (irregular pigmentation, blue-white veil, atypical network, multicomponent pattern, atypical dots and/or globules, regression, peripheral tan structureless area, negative network, shiny white structures, atypical vessels and streaks/pseudopods), with melanoma Breslow index or other histopathology characteristics (melanoma subtype, mitotic index and presence of ulceration). Two reviewers will independently screen and search results, extract data from eligible studies and assess risk of bias. The evidence derived by this study will elucidate the possible link between melanoma dermoscopy and histopathology. If we could predict melanoma thickness based on dermoscopy, we would be able to anticipate melanoma treatment with impact on survival.

Ethics and dissemination
Ethical approval is not required because this is a literature-based study. It will be published in scientific Pubmed indexed open access journals to ensure its accessibility.

PROSPERO registration number
CRD42024564919.

La campagna di Airc. Prevenzione e ricerca migliorano prognosi

Casi melanoma raddoppiati. L’esperta,’più rischi con scottature’

Ascierto, ‘obiettivo è anticipare la malattia .I 7 errori da non fare in estate’

In pazienti non diabetici. Ascierto, dieta può influenzare cure

This case report describes a woman with color change involving only the facial skin and was later found to also have inguinal lymph node and rectal mass.

This cohort study further validates the Melanoma Institute Australia sentinel node metastasis risk calculator in other non-Australian melanoma populations to evaluate its global applicability.

The Original Investigation titled “Global Applicability of a Risk Prediction Tool for Sentinel Node Positivity in Patients With Primary Cutaneous Melanoma,” published online April 9, 2025, was corrected because there was a display issue with author surname Olofsson Bagge in PubMed. This article was corrected online.

This cohort study evaluates if neighborhood deprivation is associated with thicker (greater than 2 mm) cutaneous melanoma diagnosis after controlling for individual-level characteristics in the US veteran population.

Le lesioni studiate con microscopia confocale riflettente

Grazie al progetto Telemo realizzato dal Cnr di Pisa

Ogni anno 15mila casi, fondamentale la diagnosi precoce