[Articles] The impact of biological interventions on health-related quality of life in adults with Crohn's disease: a systematic review with meta-analysis

Methodological issues in HRQoL measurement, including the need for larger sample sizes, standardized reporting, and uniform participant characteristics, contribute to the low methodological quality of current evidence on the impact of biological agents on HRQoL in CD. There is a large unmet need to investigate the association between clinical outcomes and HRQoL outcomes more thoroughly.

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Luglio 2025

Whole food diet induces remission in children and young adults with mild-moderate Crohn's disease and is more tolerable than exclusive enteral nutrition: a randomized controlled trial

Tasty&Healthy (T&H) is a whole-food diet for Crohn’s disease (CD), which excludes processed food, gluten, red meat, and dairy, without requiring formula or mandatory ingredients. TASTI-MM was a clinician-blinded, randomized-controlled trial comparing tolerability and effectiveness of T&H vs. exclusive enteral nutrition (EEN).

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Giugno 2025

Defining Mucocutaneous Crohn Disease

The prevalence of Crohn disease (CD) is rising globally and therefore is of increasing relevance in the dermatology clinic. Between 14% and 44% of patients with CD demonstrate mucocutaneous involvement, which has been postulated to result from abnormal homing of gut lymphocytes to the skin.

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Giugno 2025