Uno studio osservazionale, pubblicato sulla rivista “Toxins”, ha fornito evidenze real-world sull’efficacia prolungata e sulla sicurezza della tossina botulinica di tipo A (BoNT-A) nella prevenzione della cefalea cronica, documentando miglioramenti sostenuti nel corso di un follow-up esteso.
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Infezioni sessualmente trasmissibili: troppo pochi i test nella popolazione [Infettivologia]
Presentato alla Camera il Report “Infezioni Sessualmente Trasmesse: Barriere e soluzioni della diagnosi precoce”. Partendo da due sondaggi, un Focus Group individua possibili azioni da intraprendere: maggiore informazione, interventi di prevenzione e diagnosi precoce, formazione degli operatori sanitari, un modello Hub&Spoke sul territorio
[News] Royal College of Obstetricians & Gynaecologists (RCOG) World Congress
The RCOG World Congress 2025 took place at the London ExCeL Centre on June 23–25, hosting over 2500 delegates from around 100 countries and delivering over 70 sessions with more than 220 global speakers. Under the theme of “Equity in care, innovation in action”, the programme covered an impressive range of topics, relevant to both UK and global audiences, including women’s health (eg, menopause, sexual health, inequalities in access to care, cancer, endometriosis, vulval disease, human papillomavirus (HPV) vaccination, and imaging in gynaecology), fertility and reproduction (eg, developments in assisted reproduction, abortion, and contraception), and pregnancy and post-partum care (eg, preterm birth, obstetric fistula, foetal imaging, and postpartum complications), as well as the emerging role of artificial intelligence (AI) and digital health across these topics.
Palliative Care Program for Community-Dwelling Individuals With Dementia
To the Editor The Indiana Palliative Excellence in Alzheimer Care Efforts (IN-PEACE) trial investigated the integration of palliative care within dementia care management for community-dwelling individuals with moderate to severe dementia and their caregivers. Although the trial reported a significant reduction in emergency department (ED) visits and hospitalizations, the lack of improvement in neuropsychiatric symptoms and caregiver distress raises important clinical questions.
Beyond Screen Time—Addictive Screen Use Patterns and Adolescent Mental Health
Screen use, the time spent engaging with electronic devices such as mobile phones and tablets, can become addictive when individuals experience difficulty stopping despite attempts to do so, as well as symptoms of withdrawal, tolerance, conflict, and relapse (BoxBox). Adolescence is a vulnerable period for addictive behaviors, and recent findings suggest that young adolescents are particularly susceptible to screen addiction. Notably, in the US, 48% of young adolescents report losing track of how much they are using their phone, 25% use social media to forget about their problems, and 25% admit to spending a considerable amount of time thinking about social media apps. Furthermore, 17% have tried to reduce their social media use but cannot, and 11% acknowledge that their screen use has negatively affected their schoolwork. These statistics highlight the need to study screen addiction and its specific health effects, as understanding these behaviors is crucial for addressing the risks they pose to adolescents’ well-being.
What Makes Data Meaningful
As the frontiers of health care expand, research published in medical journals like JAMA often features large-scale, international, multicenter trials and far-reaching topics, such as genomics and artificial intelligence. However, the need for individual participants to constitute vast datasets remains foundational. Tapping poetry’s capacity for expressing the uniqueness of voice and engendering empathy, the poem “Death equals one” invites readers to reflect on what makes scientific inquiry so valuable by doing something that it intentionally does not: humanize a piece of data. The poem depicts a lone epidemiologist as she studies a data point. She fixates on this “single line in the database,” initially seeing it as merely helpful information for her research. As we read, however, poetry allows us to learn more about who this data point actually is. In this poetically informed, unmasked world, both we and the speaker are humanized also. Vivid details like “never a math person” and “frail silhouette” breathe life into a person in our minds beyond “a mere string of figures.” Our materializing image of this multidimensional, not-so-hypothetical participant further contrasts with the simple equation comprising the poem’s title. The poem challenges us to remember the human beings behind the data points that we code, analyze, read, or write about. Here, poetry, in perhaps the unlikeliest of places, serves as a humbling reminder that each study participant entrusts a piece of themselves to us, to be safely and anonymously, and yet indelibly, “one among thousands” in the pursuit of inspired science.
WHO Assembly Adopts First Pandemic Agreement
Following 3 years of negotiations, member states of the World Health Organization (WHO) recently announced adoption of the first-ever international pandemic agreement.
First Blood Test for Alzheimer Biomarkers Receives FDA Clearance
This Medical News article discusses how the first FDA-cleared blood test for Alzheimer biomarkers should and shouldn’t be used.
The natural history of gastroesophageal varices in children with portal hypertension
In children with portal hypertension, the natural history of gastroesophageal varices remains unclear. We herein report our experience.
Single-Arm Trials Can Provide Randomized Real-World Evidence: The Random Invitation Single-Arm Trial Design
Annals of Internal Medicine, Ahead of Print.
[Articles] Artificial intelligence-augmented ultrasound diagnosis of follicular-patterned thyroid neoplasms: a multicenter retrospective study
Our study demonstrates that a DL-based system can provide a noninvasive, accurate, and reliable tool for the preoperative diagnosis of FNs. By improving diagnostic precision, this approach has the potential to optimize clinical decision-making and reduce the burden of overtreatment in patients with FNs. Further prospective studies are warranted to validate these findings in real-world clinical settings.
[Articles] Contemporary medical therapy, sex-specific characteristics, and outcomes of patients with non-ischemic cardiomyopathy: a prespecified interim analysis of the BIO-LIBRA study
In a contemporary cohort of patients with NICM and ICD/CRT-D, we report an increased enrollment of females and minorities, an increase in the use of novel guideline-directed medical therapy (GDMT) over time, and a lower risk of ventricular arrhythmias or death in females as compared to men at one year.
Ruxolitinib crema nella vitiligine: efficacia reale oltre i dati clinici. #ICD2025 [Dermatologia]
A un anno dall’introduzione di ruxolitinib crema, primo trattamento topico specifico per la vitiligine non segmentale, si apre un nuovo capitolo nella gestione clinica della malattia. In occasione dell’incontro scientifico Sharing Real Practice in Vitiligo: Beyond Clinical Data, svoltosi durante il XIV International Congress of Dermatology, sono state condivise esperienze, casi clinici e dati real-world, confrontando l’efficacia terapeutica osservata nella pratica quotidiana con i risultati degli studi di fase 3.
Alzheimer, a Milano si riunisce un'alleanza internazionale per affrontare la sfida comune #MindtheFuture [Neurologia e Psichiatria]
Quali strategie e politiche dovranno essere messe in atto a livello internazionale per affrontare quella che è stata definita una vera e propria pandemia del nuovo millennio? A queste e molte altre domande ha cercato di rispondere l’evento “MIND THE FUTURE – A CROSS COUNTRY ALZHEIMER READINESS PACT”, promosso dalla Fondazione della Sostenibilità Sociale, con il patrocinio della Società Italiana di Farmacologia e il supporto non condizionante di Lilly Italia, GE Healthcare, Biogen, Siemens e Fujirebio — che si è articolato in due giornate di lavoro che hanno preso avvio nella cornice istituzionale di Regione Lombardia e si sono concluse presso Università Vita Salute San Raffaele.
Gestione delle infezioni sessualmente trasmissibili asintomatiche: linee guida
Le linee guida dell’OMS per la gestione delle infezioni sessualmente […]
XI Rapporto UNIAMO sulla condizione delle persone con malattia rara [Malattie Rare]
Presentato ieri a Roma, alla presenza di numerosi rappresentanti istituzionali, autorevoli componenti della comunità scientifica e delle Associazioni, l’XI Rapporto MonitoRare sulla condizione delle persone con malattia rara in Italia. Dal 2015 la Federazione UNIAMO – unico caso in Europa e nel mondo – grazie alla collaborazione con le Istituzioni, raccoglie e analizza i dati disponibili per dare vita a un documento che offre una visione globale del sistema malattie rare, partendo dal punto di vista del persona con malattia rara.