Maria Van Kerkhove, responsabile tecnico per Covid-19 all’Oms: «I casi e i ricoveri per Covid sono in aumento da mesi»
Risultati per: Papilloma virus
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Live-Virus Shingles Vaccine Provided Some Long-Term Protection
New results suggest that a live-virus vaccine intended to protect against shingles—a condition caused by reactivation of the varicella-zoster virus, which also causes chickenpox—prevented illness in 67% of people in the first year after vaccination. But after 10 years, the vaccine’s efficacy against shingles, also known as herpes zoster, had declined to 15%. The study used electronic health record data from more than 500 000 adults aged 50 years or older who received the shot between 2007 and 2018 in California.
Ecdc agli Stati, agire subito contro i virus respiratori
Rafforzare le vaccinazioni e la capacità ospedaliera
Antibody Titers against Mpox Virus after Vaccination
New England Journal of Medicine, Volume 389, Issue 24, Page 2299-2301, December 2023.
Acute Human Immunodeficiency Virus Infection
New England Journal of Medicine, Volume 389, Issue 24, Page 2276-2276, December 2023.
Efsa, nel 2022 picco del virus del Nilo occidentale
Oltre mille i casi in Europa, secondo anno record dopo il 2018
Replication-Competent Virus Detected in Blood of a Fatal COVID-19 Case
Annals of Internal Medicine, Ahead of Print.
Replication-Competent Virus Detected in Blood of a Fatal COVID-19 Case
Annals of Internal Medicine, Ahead of Print.
Changing prevalence of chronic hepatitis B virus infection in China between 1973 and 2021: a systematic literature review and meta-analysis of 3740 studies and 231 million people
Objective
China concentrates a large part of the global burden of HBV infection, playing a pivotal role in achieving the WHO 2030 global hepatitis elimination target.
Methods
We searched for studies reporting HBV surface antigen (HBsAg) seroprevalence in five databases until January 2023. Eligible data were pooled using a generalised linear mixed model with random effects to obtain summary HBsAg seroprevalence. Linear regression was used to estimate annual percentage change (APC) and HBsAg prevalence in 2021.
Results
3740 studies, including 231 million subjects, were meta-analysed. HBsAg seroprevalence for the general population decreased from 9.6% (95% CI 8.4 to 10.9%) in 1973–1984 to 3.0% (95% CI 2.1 to 3.9%) in 2021 (APC=–3.77; p
Annals On Call – Protecting Adults Against Respiratory Syncytial Virus Infection
Annals of Internal Medicine, Volume 176, Issue 11, November 2023.
Annals On Call – Protecting Adults Against Respiratory Syncytial Virus Infection
Annals of Internal Medicine, Volume 176, Issue 11, November 2023.
Usutu virus, nuovi casi in storni e zanzare in Sardegna
A Oristano e Arborea, Asl ‘situazione sotto controllo’
Oncologi ai pazienti, 'vaccinarsi contro il Covid, il virus è ancora pericoloso'
Campagna Aiom su vaccinazioni, 80% malati non conosce i vantaggi
Chronic Hepatitis B Virus Infection and Risk of Stroke Types: A Prospective Cohort Study of 500 000 Chinese Adults
Stroke, Ahead of Print. BACKGROUND:Stroke is a leading cause of mortality and permanent disability in China, with large and unexplained geographic variations in rates of different stroke types. Chronic hepatitis B virus infection is prevalent among Chinese adults and may play a role in stroke cause.METHODS:The prospective China Kadoorie Biobank included >500 000 adults aged 30 to 79 years who were recruited from 10 (5 urban and 5 rural) geographically diverse areas of China from 2004 to 2008, with determination of hepatitis B surface antigen (HBsAg) positivity at baseline. During 11 years of follow-up, a total of 59 117 incident stroke cases occurred, including 11 318 intracerebral hemorrhage (ICH), 49 971 ischemic stroke, 995 subarachnoid hemorrhage, and 3036 other/unspecified stroke. Cox regression models were used to estimate adjusted hazard ratios (HRs) for risk of stroke types associated with HBsAg positivity. In a subset of 17 833 participants, liver enzymes and lipids levels were measured and compared by HBsAg status.RESULTS:Overall, 3.0% of participants were positive for HBsAg. HBsAg positivity was associated with an increased risk of ICH (adjusted HR, 1.29 [95% CI, 1.16–1.44]), similarly for fatal (n=5982; adjusted HR, 1.36 [95% CI, 1.16–1.59]) and nonfatal (n=5336; adjusted HR, 1.23 [95% CI, 1.06–1.44]) ICH. There were no significant associations of HBsAg positivity with risks of ischemic stroke (adjusted HR, 0.97 [95% CI, 0.92–1.03]), subarachnoid hemorrhage (adjusted HR, 0.87 [95% CI, 0.57–1.33]), or other/unspecified stroke (adjusted HR, 1.12 [95% CI, 0.89–1.42]). Compared with HBsAg-negative counterparts, HBsAg-positive individuals had lower lipid and albumin levels and higher liver enzyme levels. After adjustment for liver enzymes and albumin, the association with ICH from HBsAg positivity attenuated to 1.15 (0.90–1.48), suggesting possible mediation by abnormal liver function.CONCLUSIONS:Among Chinese adults, chronic hepatitis B virus infection is associated with an increased risk of ICH but not other stroke types, which may be mediated through liver dysfunction and altered lipid metabolism.
Prevalence and determinants of high-risk human papilloma virus among men who have sex with men in Benin: a cross-sectional study embedded in a demonstration project on pre-exposure prophylaxis against HIV
Objectives
This study aims to assess the prevalence and factors associated with anal high-risk human papilloma virus (HR-HPV).
Design
A cross-sectional study conducted from 24 August 2020 to 24 November 2020.
Setting
Primary care, Cotonou, Benin.
Participants
204 HIV-negative men who have sex with men initiating oral pre-exposure prophylaxis.
Primary outcome measure
Anal HR-HPV genotypes using GeneXpert HPV assay. Fourteen HR-HPV were evaluated: HPV-16 and HPV-18/45 in 2 distinct channels and the 11 other genotypes as a pooled result (31, 33, 35, 39, 51, 52, 56, 58, 59, 66 and 68). The potential independent variables analysed included anal gonorrhoea and chlamydia infections, and sociodemographic and sexual behaviour factors. To assess the determinants of HR-HPV, univariate and multivariate Poisson regression models were performed by using SAS V.9.4.
Results
Mean age±SD was 25.9±4.8 years. 131/204 men claimed insertive sex procured more pleasure. Thirty-two participants, accounting for 15.7% of the study sample, had gonorrhoea and/or chlamydia. The prevalence of any HR-HPV genotype was 36.3% (95% CI 30.0% to 43.0%). In total, 7.8% of men had HPV-16 and 7.4% had HPV-18/45. The prevalence for the pooled genotypes (31, 33, 35, 39, 51, 52, 56, 58, 59, 66 and 68) was 29.9%. Receptive anal sex during the last 6 months was strongly associated with prevalent HR-HPV infections. The adjusted proportion ratio (aPR) was 1.93 (95% CI 1.31 to 2.83). Gonorrhoea and chlamydia were also associated with the outcome of interest; p value for both infections was
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