In a comparative study, AI-generated and physician-written summaries each had unique strengths and weaknesses.
Risultati per: Probiotici: in vivo vs in vitro
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Emergency Department Visits for Medication-Related Events With vs Without Pharmacist Intervention
This randomized clinical trial assesses the efficacy of a pharmacist-led transition of care program in reducing emergency department visits related to the same medication-related event at 6 months compared with usual care.
Standard Dermatoscope Images vs an Autonomous Total Body Photography and Dermoscopic Imaging Device
This cohort study examines the imaging quality and time efficiency of a novel autonomous total body photographic and dermoscopic device compared with traditional manual digital dermoscopic imaging.
Oral vs Extended-Release Injectable Naltrexone for Hospitalized Patients With Alcohol Use Disorder
This randomized clinical trial compares the effectiveness of initiating oral naltrexone vs extended-release injectable naltrexone on reduction in alcohol use and health care utilization among medical inpatients with alcohol use disorder.
Functional vs Structural Cortical Deficit Pattern Biomarkers for MDD
This case-control study investigates if a regional homogeneity–magnetic resonance imaging cortical deficit pattern provides a more robust biomarker for major depressive disorder (MDD) than its structural counterpart and informs the underlying, regionally specific lower cerebral blood flow in this disorder.
Camrelizumab vs Placebo in Patients With Triple-Negative Breast Cancer
To the Editor A recent trial reported that camrelizumab in combination with chemotherapy significantly improved the pathological complete response (pCR) compared with placebo in combination with chemotherapy among patients with early or locally advanced triple-negative breast cancer (TNBC), with pCR rates of 56.8% vs 44.7%, respectively. However, the 18-month event-free survival rates were 86.6% vs 83.6% (hazard ratio, 0.80 [95% CI, 0.46-1.42]), showing no statistical significance, and the wide CI indicates that the study had a relatively short follow-up period and immature survival data.
Camrelizumab vs Placebo in Patients With Triple-Negative Breast Cancer—Reply
In Reply We appreciate the comments by Dr Pei about our recent phase 3 trial, CamRelief.
Prothrombin Complex Concentrate vs Frozen Plasma in Cardiac Surgery
This clinical trial compares the efficacy and safety of prothrombin complex concentrate with frozen plasma in patients requiring coagulation factor replacement for bleeding during cardiac surgery.
Microultrasonography-Guided vs MRI-Guided Biopsy for Prostate Cancer Diagnosis
This randomized, noninferiority trial of biopsy-naive men compares the detection of Gleason Grade Group ≥2 prostate cancer using microultrasonography-guided and MRI fusion-guided biopsy.
Tirzepatide vs. Semaglutide for Patients with Obesity: A Head-to-Head Trial
At 72 weeks, percentage decrease in weight was greater with tirzepatide.
Patient-Specific In Vivo Gene Editing to Treat a Rare Genetic Disease
New England Journal of Medicine, Ahead of Print.
In ischemic stroke, IV thrombolysis >4.5 h after symptom onset vs. standard medical care improves 90-d functional outcomes
Annals of Internal Medicine, Ahead of Print.
In adults with overweight or obesity and without diabetes, GLP-1 RAs increase weight loss vs. placebo
Annals of Internal Medicine, Ahead of Print.
In patients with subclinical AF, apixaban vs. aspirin reduced stroke or systemic embolism at 3.5 y in those with previous stroke or TIA
Annals of Internal Medicine, Ahead of Print.
In early postmenopausal women, zoledronate vs. placebo at baseline and 5 y reduced morphometric vertebral fractures at 10 y
Annals of Internal Medicine, Ahead of Print.
In AF with recent ACS or PCI, apixaban reduced total bleeding vs. VKA; aspirin increased total bleeding vs. placebo at 6 mo
Annals of Internal Medicine, Ahead of Print.