Questo è quello che abbiamo trovato per te
This phase 2 randomized clinical trial evaluates whether the addition of vistusertib to weekly paclitaxel improves clinical outcomes in patients with platinum-resistant ovarian high-grade serous carcinoma.
This survey study evaluate the association of patients’ health care values with engagement in advance care planning and end-of-life care.
Noting that randomized clinical trials (RCTs) “generally yield the strongest inferences about the effects of medical treatments,”(p984) the AMA Manual of Style instructs that “randomized trials may use terms such as effect and causal relationship,”(p983) In contrast, the manual claims that observational studies “cannot lead to causal inferences”(p994) and thus “should be described in terms of association or correlation and should avoid cause-and-effect wording.”(p983) Nevertheless, analyses of observational data—often consisting of real-world evidence from databases of medical claims and electronic health records—play an increasingly prominent role in health care. Given the well-recognized limitations of observational studies, their growing use to estimate treatment effects is the subject of considerable controversy. Should real-world evidence have a meaningful role in decision-making? In this issue of JAMA, investigators from the RCT DUPLICATE Initiative address this controversy by directly comparing the results of published RCTs to analyses of 3 national claims databases that are carefully designed to emulate the original RCTs. The results of their productive line of research warrant careful consideration.
This randomized clinical trial assesses the effect of adding panitumumab vs bevacizumab to standard first-line chemotherapy on overall survival among patients with RAS wild-type, left-sided, metastatic colorectal cancer.
Oggi Giornata mondiale; Fedemo, più risorse strutturali e umane
Progetto di musicoterapia con Allieve Santa Cecilia e Neuchatel
Più difese immunitarie, meno antidolorifici e ricoveri più brevi
Per immunoterapia più efficace. Int guida progetto internazionale
This randomized clinical trial among patients with incomplete spontaneous abortion but intending future conception compares rates of subsequent pregnancy at 2-year follow-up after receiving vacuum aspiration vs hysteroscopy.
Among people with Medicare insurance, more than 40% chose phone visits over video visits.
New England Journal of Medicine, Volume 388, Issue 14, Page 1341-1342, April 2023.
Annals of Internal Medicine, Ahead of Print.
Annals of Internal Medicine, Ahead of Print.
Annals of Internal Medicine, Ahead of Print.
Annals of Internal Medicine, Ahead of Print.
Annals of Internal Medicine, Ahead of Print.
