Autore/Fonte: Cleveland Clinic
Sildenafil come potenziale trattamento per il morbo di Alzheimer
Leggi →
9 Marzo 2024
Questo è quello che abbiamo trovato per te
Autore/Fonte: Cleveland Clinic
La conferma potrebbe arrivare in coincidenza con la festa della donna, il prossimo 8 marzo, quando il ministro della Salute Schillaci potrebbe svelarne il nome
A Bologna un evento per fare il punto della situazione
Annals of Internal Medicine, Ahead of Print.
Annals of Internal Medicine, Ahead of Print.
Objectives
Current mental health practices for people living in residential aged care (RAC) facilities are poor. In Australia, there are no mechanisms to monitor and promote mental health for people living in RAC, including those who experience changed behaviours and psychological symptoms. The aim of this study is to improve current practices and mental health outcomes for people living in RAC facilities by codesigning a Mental Health benchmarking Industry Tool for residential aged Care (MHICare Tool).
Methods
A two-stage sequential and mixed methods codesign methodology will be used. Stage 1 will include qualitative interviews and focus groups to engage with residents, family/care partners and RAC staff to ascertain mental healthcare practices and outcomes of greatest significance to them. Adapted concept mapping methods will be used to rank identified issues of concern in order of importance and changeability, and to generate draft quality indicators. Stage 2 will comprise a Delphi procedure to gain the wider consensus of expert panel views (aged care industry, academic, clinical) on the performance indicators to be included, resulting in the codesigned MHICare Tool.
Ethics and dissemination
This study has been reviewed and approved by the University of Queensland Human Research Ethics Committee (HREC/2019002096). This project will be carried out according to the National Statement on Ethical Conduct in Human Research (2007). The study’s findings will be published in peer-reviewed journals and disseminated at national and international conferences and through social media.
Conclusion
This protocol reports structured methods to codesign and develop a mental health performance indicator tool for use in Australian RAC.
Sidhu R, Turnbull D, Haboubi H, et al. British Society of Gastroenterology guidelines on sedation in gastrointestinal endoscopy. Gut 2024;73:219-45. doi: 10.1136/gutjnl-2023-330396
During the peer review process, the following statement was altered. We would like to issue a correction to Statement 10 in relation to monitoring requirements during endoscopy.
This should read:
Procedure Room Requirements
We recommend all patients undergoing gastrointestinal endoscopy (sedated or unsedated) have continuous monitoring of pulse, blood pressure, oxygen saturations and respiration rates as. We recommend supplemental oxygen where any level of sedation is used.
Grade of Evidence: Very Low. Strength of Recommendation: Strong.
Level of Agreement: 100%
Autore/Fonte: The Annals of Thoracic Surgery
New England Journal of Medicine, Volume 390, Issue 6, Page 549-556, February 2024.
Introduction
Air pollution is a global issue that poses a significant threat to public health. Children, due to their developing physiology, are particularly susceptible to the inhalation of environmental pollutants. Exposure can trigger immune modulation and organ damage, increasing susceptibility to respiratory diseases. Therefore, we aim to examine the association between heavy metal and particulate matter exposure with tuberculosis in children.
Methods and analysis
As a case–control study, we will include children diagnosed with pulmonary tuberculosis (n=60) and matched healthy controls (n=80) recruited from the same communities in Dhaka, Bangladesh. Exposure data for both cases and controls will be collected by a trained field team conducting home visits. They will administer an exposure questionnaire, measure child anthropometry, collect blood and household dust samples and instal 48-hour air quality monitors. The blood samples will be analysed by inductively coupled plasma mass spectrometry for serum heavy metal concentrations (lead, cadmium, arsenic, mercury and chromium), as a representative marker of exposure, and the presence of inflammatory biomarkers. Descriptive and inferential statistics, including independent samples t-tests, analysis of variance and conditional regression analysis, will be used to quantify heavy metal and particulate matter exposure status in tuberculosis cases compared with healthy controls, while accounting for potential confounders. Dust samples and air quality results will be analysed to understand household sources of heavy metal and particulate matter exposure. To test the study hypothesis, there is a positive association between exposure and tuberculosis diseases, we will also measure the accumulated effect of simultaneous exposures using Bayesian statistical modelling.
Ethics and dissemination
This study has been approved by International Centre for Diarrhoeal Disease Research, Bangladesh’s Institutional Review Board (PR-22030). The study findings will be disseminated at conferences and published in peer-reviewed journals.
Stroke, Volume 55, Issue Suppl_1, Page AWP259-AWP259, February 1, 2024. Background:Stroke is a major cause of maternal morbidity and mortality, but delays in diagnosis are common. We hypothesize that in individuals who are pregnant or within 1 year postpartum (PP), the triad of early PP state (first 6 weeks after delivery), elevated blood pressure (BP), and headache is associated with higher stroke risk.Methods:We conducted a single-institution case-control study. Cases had a maternal stroke (ischemic, hemorrhagic, subarachnoid hemorrhage, or cerebral venous thrombosis) during pregnancy or PP, identified from a stroke registry. Controls were pregnant or PP but without any stroke and admitted for any reason, identified from a cohort of individuals with a high proportion of hypertensive disorders of pregnancy (HDP), a known maternal stroke risk factor. We created multivariable logistic regression models with stepwise backward elimination to evaluate the association between maternal stroke and the triad of (1) early PP; (2) systolic BP ≥140 or diastolic ≥90 mmHg; and (3) headache.Results:We identified 60 cases and 113 controls. Population characteristics are shown in the Table. Cases had a higher proportion of preexisting headache disorders and controls a had higher proportion of HDP. Adjusting for race, HDP, and headache disorder history, stroke risk was higher in those presenting to acute care with the proposed triad than in those without these features (adjusted odds ratio 13.6, 95% confidence interval 3.8-48.5, p
Stroke, Volume 55, Issue Suppl_1, Page ATMP71-ATMP71, February 1, 2024. Background and aim:Significant headache is often reported by patients with moyamoya arteriopathy (MMA) but has a poorly understood pathophysiology. To decide on management, physicians often focus on stroke-like symptoms while the impact on quality of life and economic burden of chronic headache is often overlooked. We aimed to investigate the effect of revascularization surgery on headache in MMA and potential association with cerebrovascular reactivity (CVR).Methods:This was a single-center retrospective study in adult patients with MMA, who underwent extracranial-intracranial (EC-IC) bypass surgery between Jan 2010 – Sept 2022 and had CVR-MRI performed. Clinical and imaging data were collected through systematic chart review complemented by structured headache questionnaires. We assessed the association between headache and CVR before and after revascularization surgery along with potential predictors using logistic regression analysis.Results:Fifty-nine patients were included (mean age 44±13 years, 42 women (71%)). Thirty-seven patients (63%) had bilateral MMA of whom 19 (51%) had bilateral EC-IC bypass surgery. Thirty-eight patients (64%) reported headache pre-surgery with mostly migraine-like features. More than a third of patients (37%) lost workdays or quit their job because of headache. Headache improved in 26/38 (68%) patients post-surgery with a reduction in pain severity (median VAS 6 to 3; p = 0.005) and sick leave (37% to 8%; p
This systematic review and meta-analysis explores the potential role of socioeconomic position in the association between mental disorders and mortality as well as the association between socioeconomic position and mortality among individuals with mental disorders.
Fondazione Onda e Anircef insieme per nuovo percorso di cura
Fondazione Onda e Anircef insieme per nuovo percorso di cura
Objectives
This study aimed to examine the prevalence of post-traumatic stress disorder (PTSD) in victims-survivors of intimate partner violence (IPV) consulting at the specialised and original facility ‘Maison des Femmes’ (MdF) or in two close municipal health centres (MHCs).
Design
A mixed-methods study using a convergent parallel design from July 2020 to June 2021.
Setting/participants
A questionnaire was proposed to women aged 18 years and over having suffered from IPV, in the MdF and in two MHCs. We also conducted qualitative interviews with a subsample of the women, asking for victim-survivors’ perceptions of the effect of the MdF’s care.
Primary and secondary outcome measures
The presence of a PTSD using the PTSD self-report checklist of symptoms, possibility of reaching women by phone 6 months after the inclusion visit, level of self-rated global health, number of emergency visits in the past 6 months, substances use, readiness to change and safety behaviours.
Results
A total of 67 women (mean age: 34 years (SD=9.7)) responded to our questionnaire. PTSD diagnosis was retained for 40 women (59.7%). Around 30% of participants self-rated their global health as bad. Less than 30% (n=18) of women were regular smokers, and only 7.5% of participants had a problematic alcohol use (Alcohol Use Disorders Identification Test-Consumption score ≥4), 19.4% women used psychotropic drugs. Six months after inclusion, half of participants had been reached by phone. Analysis of the qualitative interviews clarified victim-survivors’ perceptions of the MdF’s specific care: social networking, multidisciplinary approach, specialised listening, healthcare facilities, evasion and ‘feeling at home’.
Conclusions
The high prevalence of PTSD at inclusion was nearly the same between the three centres. This mixed-methods comparison will serve as a pilot study for a larger comparative trial to assess the long-term impact of the MdF’s specialised care on victims-survivors’ mental health, compared with the care of uncoordinated structures.
Trial registration number
NCT04304469.