Risultati per: L’alcool danneggia il DNA e aumenta il rischio di cancro.

Studio,connessione tra perdita e problemi salute

Cardiologo, ‘no agli integratori, sì al consumo programmato di acqua’

Confindustria: “causerà una crisi irrevesibile”. Giani: “così abbassiamo l’Irpef”

Nei frutti di mare, proliferazione legata ad aumento temperature

Studio dell’Università di Bologna, efficace al 50% e sicuro

Le forme più gravi aumentano ancora di più il pericolo

Studio, anche meno ricoveri e farmaci

Aggiornamento del bollettino del ministero della Salute

Esophageal, colorectal, pancreatic, hepatocellular, and gastric cancer together impact millions of patients worldwide each year, with high overall mortality rates and are increasing in incidence. Additionally, premalignant gastrointestinal diseases such as Barrett’s esophagus and inflammatory bowel disease are also increasing in incidence. However, involvement of aberrant DNA methylation in these diseases is incompletely understood, especially given recent research advancements in this field. Here, we review knowledge of this epigenetic mechanism in gastrointestinal preneoplasia and neoplasia, considering mechanisms of action, genetic and environmental factors, and CpG island methylator phenotype.

In the Original Investigation titled “Neoadjuvant Nivolumab Plus Chemotherapy Followed by Response Adaptive-Therapy for HPV+ Oropharyngeal Cancer: OPTIMA II Phase 2 Open-Label Nonrandomized Clinical Trial,” published online on June 6, 2024, in JAMA Oncology, Figure 4 contained transposed labels on the curves in panel B, and the DNA Safe-Sequencing System was not accurately attributed to Sysmex Inostics Inc. This article was corrected online.

This nonrandomized controlled trial assesses the feasibility of using a circulating tumor DNA−guided adaptive de-escalation tyrosine kinase inhibitor strategy in patients with advanced non−small cell lung cancer to achieve complete remission after local consolidative therapy.

New England Journal of Medicine, Volume 390, Issue 23, Page 2222-2225, June 20, 2024.