Rare cause of obstructive jaundice

Introduction An 85-year-old woman, with a high-grade fever (40°C) and abdominal pain, was referred to our hospital. Blood examination revealed an elevated white blood cell count (25.8×10/L) and elevated levels of C reactive protein (8.54 mg/dL), alanine aminotransferase (95 IU/L), aspartate transaminase (138 IU/L), alkaline phosphatase (804 IU/L), gamma-glutamyl transpeptidase (703 IU/L), and total (5.0 mg/dL) and direct (3.2 mg/dL) bilirubin. Contrast-enhanced CT (CECT) was performed (figure 1). Question What is the diagnosis? Answer CECT revealed a massive paraesophageal hernia, with prolapse of the stomach, duodenum and pancreatic head. Obstructive jaundice was accompanied by a mesenteric gastric volvulus (figure 2). An emergency endoscopy was performed to release the volvulus. Although the endoscope could reach the fourth portion of the duodenum, the pancreatic head remained locked within the hernial sac, and endoscopic detorsion could not be performed (figure 3). As the forward-viewing endoscope could enable frontal…

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Maggio 2024

Neurological Conditions Are Leading Cause of Disability Worldwide

More than 3 billion people—about 43% of the global population—lived with neurological conditions in 2021, according to results from the Global Burden of Disease Study published in The Lancet Neurology. Although this represented an 18.2% increase from 1990, once researchers adjusted for age, they found that the prevalence of neurological conditions rose by about 1.5% over the past 2 decades.

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Maggio 2024