Risultati per: Nanotubi di DNA per terapie contro i tumori del cervello

Consiste nella rottura fatale di un vaso sanguigno nel cervello

Nel 2024 6mila diagnosi in Italia, radioterapia strategia chiave

Nel 2024 6mila diagnosi in Italia, radioterapia strategia chiave

L’esperta: resta un test fondamentale ma l’abuso è causa del 5% dei casi

Usata per annunciare un trattamento sanitario o la guarigione

Usata per annunciare un trattamento sanitario o la guarigione

New England Journal of Medicine, Volume 392, Issue 14, Page 1447-1450, April 10, 2025.

Licenziamenti rallentano i progressi del National Institutes of Health

Dopo la Nave per la salute, in 2 giorni 370 visite e test gratis

Iniziativa a cura dell’Unità operativa Oncologica del Profili

This narrative review explores how the identification of measurable residual disease through methods of detecting circulating tumor DNA contributes to outcomes for B-cell lymphomas.

Un ANSA Incontra con i ricercatori sulla ricerca di frontiera

Cipomo, ‘possibile antidoto contro burnout e aggressioni’

Introduction
Cervical cancer remains a significant public health concern in Singapore, with current screening rates at 43%, well below the national target of 70%. In 2019, human papillomavirus (HPV) DNA testing was introduced into the national cervical cancer screening programme, but barriers to participation include embarrassment, privacy concerns and discomfort with clinician-sampled tests. Self-sampled HPV DNA testing offers a promising alternative by providing more privacy and convenience. This study aims to evaluate the impact of including self-sampled HPV DNA testing as an alternative to clinician-sampling on screening uptake, clinical outcomes and cost-effectiveness in primary care.

Methods and analysis
This pragmatic, open-label, two-arm randomised controlled trial employs a Zelen design. A total of 650 women aged 30–69 who are due for cervical cancer screening will be recruited from National Healthcare Group Polyclinics in Singapore. Participants will be randomly assigned to either the intervention arm (offering both self-sampling and clinician-sampling) or the usual care arm (clinician-sampling only). The primary outcome is the proportion of participants in each arm detected with high-risk HPV. Secondary outcomes include the proportion of participants in each arm who undergo cervical cancer screening (uptake), are referred for colposcopy and are detected with CIN 2/3 or cervical cancer, as well as cost-effectiveness. Acceptability and feasibility of self-sampling will be evaluated through post-screening questionnaires.

Ethics and dissemination
Ethical approval was granted by the National Healthcare Group Domain Specific Review Board. Study results will be disseminated through peer-reviewed journals, healthcare conferences and shared with policymakers to guide potential inclusion of self-sampling in Singapore’s national cervical cancer screening programme. Findings from this trial will provide crucial evidence for the potential inclusion of self-sampling in Singapore’s national cervical cancer screening programme, which could increase screening rates and improve public health outcomes.

Trial registration number
ClinicalTrials.gov: NCT06528184.

Lo aveva presentato la maggioranza. M5s: ‘Però usano soldi per le armi’