Risultati per: Uso dei test del DNA tumorale circolante per i pazienti con cancro

Stima l’età del cuore e il rischio di infarto e ictus usando ECG

Annals of Internal Medicine, Ahead of Print.

Introduction
Cervical cancer remains a significant public health concern in Singapore, with current screening rates at 43%, well below the national target of 70%. In 2019, human papillomavirus (HPV) DNA testing was introduced into the national cervical cancer screening programme, but barriers to participation include embarrassment, privacy concerns and discomfort with clinician-sampled tests. Self-sampled HPV DNA testing offers a promising alternative by providing more privacy and convenience. This study aims to evaluate the impact of including self-sampled HPV DNA testing as an alternative to clinician-sampling on screening uptake, clinical outcomes and cost-effectiveness in primary care.

Methods and analysis
This pragmatic, open-label, two-arm randomised controlled trial employs a Zelen design. A total of 650 women aged 30–69 who are due for cervical cancer screening will be recruited from National Healthcare Group Polyclinics in Singapore. Participants will be randomly assigned to either the intervention arm (offering both self-sampling and clinician-sampling) or the usual care arm (clinician-sampling only). The primary outcome is the proportion of participants in each arm detected with high-risk HPV. Secondary outcomes include the proportion of participants in each arm who undergo cervical cancer screening (uptake), are referred for colposcopy and are detected with CIN 2/3 or cervical cancer, as well as cost-effectiveness. Acceptability and feasibility of self-sampling will be evaluated through post-screening questionnaires.

Ethics and dissemination
Ethical approval was granted by the National Healthcare Group Domain Specific Review Board. Study results will be disseminated through peer-reviewed journals, healthcare conferences and shared with policymakers to guide potential inclusion of self-sampling in Singapore’s national cervical cancer screening programme. Findings from this trial will provide crucial evidence for the potential inclusion of self-sampling in Singapore’s national cervical cancer screening programme, which could increase screening rates and improve public health outcomes.

Trial registration number
ClinicalTrials.gov: NCT06528184.

Un documento e tre cortometraggi per dare loro voce. ‘Più cura, più tempo, più vita’, da case manager a sessualità

Marzi: “Definito un approccio inclusivo, nuovo e indispensabile”

Studio, una bevanda al giorno aumenta il rischio di 5 volte

Studio, una bevanda al giorno aumenta il rischio di 5 volte

Concerti organizzati dall’Irccs e dal Conservatorio di Potenza

Tra primi 5 al mondo in ricerca. Corso con Società oncologi Usa

Objective
To determine the cost-effectiveness of the QuantiFERON (QFT) test versus the tuberculin skin test (TST) in diagnosing latent tuberculosis infection (LTBI) in immunocompetent children under 15 years of age who are in contact with active tuberculosis (TB) patients in the context of the Colombian healthcare system.

Design
Health economic evaluation. Decision tree over a horizon of

Montezemolo, usato solo da Lombardia e Toscana, non mi sta bene

Minore diffusione al Sud per la qualità di una molecola

Disegni con messaggi, consigli e poesie per il Pontefice

Effetti anche dopo 20 anni. Parte reclutamento in 7 regioni

Per la prevenzione del cancro dell’intestino

Per la prevenzione del cancro dell’intestino