We read with utmost interest the study by Zhou et al,1 which was the first family-based investigation of Helicobacter pylori (Hp) infection in China. The authors provided valuable insights into the occurrence of familial cluster effect on Hp infection and the superiority of the ‘family-based strategy’. However, their work failed to compare the screening efficiency of various established Hp management methods, leaving us curious about whether the ‘family-based strategy’ could identify more Hp-infected participants with equal number of tests conducted as compared with the widely used ‘test and treat strategy’.2 Fortunately, the family-unit data in Zhou’s study offers the possibility for such exploration. To address this gap, we built a database consisting of over one million households, based on the infection status of households and individuals from 29 provinces reported by Zhou, in order to simulate real-world scenarios. The screening protocols were simulated in national…
Risultati per: Nuovo test per distinguere tra infezioni virali e batteriche
Questo è quello che abbiamo trovato per te
Attività motoria dalla scuola d'infanzia, test in Emilia-Romagna
Iniziativa apripista, saranno coinvolti 2.500 bimbi di 4-5 anni
Celiac disease-related conditions: Who to test?
Celiac disease (CeD) is a chronic immune-mediated condition triggered by gluten consumption in genetically predisposed individuals. Approximately 1% of the general population is affected by the disorder. Disease presentation is heterogeneous, and despite growing awareness among physicians and the public, it continues to be underestimated. The most effective strategy for identifying undiagnosed CeD is proactive case-finding through serologic testing in high-risk groups. We reviewed the most recent evidence on the association between CeD and over 20 conditions.
Prevalence of Sessile Serrated Lesions in Individuals with Positive Fecal Immunochemical Test Undergoing Colonoscopy: Results from a Large Nationwide Veterans Affairs Database
Ogni anno 12.000 decessi per infezioni resistenti a antibiotici
A Torino primo evento della campagna Diagnostica e prevenzione
Commercial Blood Test May Identify Alzheimer Disease Brain Pathology
A commercially available blood test that measures levels of a tau protein known as phosphorylated tau 217, or p-tau217, was able to identify people whose brains showed signs of Alzheimer disease pathology, according to data from an observational study. The research involved about 800 participants with and without cognitive impairment.
Diagnostic performance evaluation of urine HIV-1 antibody rapid test kits in a real-life routine care setting in China
Objectives
To evaluate the diagnostic performance of urine HIV antibody rapid test kits in screening diverse populations and to analyse subjects’ willingness regarding reagent types, purchase channels, acceptable prices, and self-testing.
Designs
Diagnostic accuracy studies
Participants
A total of 2606 valid and eligible samples were collected in the study, including 202 samples from female sex workers (FSWs), 304 persons with injection drug use (IDU), 1000 pregnant women (PW), 100 subjects undergoing voluntary HIV counselling and testing (VCT) and 1000 students in higher education schools or colleges (STUs). Subjects should simultaneously meet the following inclusion criteria: (1) being at least 18 years old and in full civil capacity, (2) signing an informed consent form and (3) providing truthful identifying information to ensure that the subjects and their samples are unique.
Results
The sensitivity, specificity and area under the curve (AUC) of the urine HIV-1 antibody rapid test kits were 92.16%, 99.92% and 0.960 (95% CI: 0.952 to 0.968, p
Morbillo, nell'area di Milano nuova variante che può sfuggire a test
Studio, individuati 5 casi, analogie con contagi in Svizzera
Dalle infezioni resistenti costi per un miliardo l'anno
Cittadinanzattiva lancia una Roadmap con 10 priorità
Verso un test delle urine per la diagnosi precoce del cancro alle ovaie
Miglioramento della sopravvivenza a 5 anni se il tumore è in fase precoce
Colonoscopy vs. the Fecal Immunochemical Test: Which is Best?
While there is no debate around the effectiveness of colorectal cancer (CRC) screening in reducing disease burden, there remains a question regarding the most effective and cost-effective screening modality. Current United States guidelines present a panel of options that include the two most commonly used modalities, colonoscopy and stool testing with the fecal immunochemical test (FIT). Large-scale comparative effectiveness trials comparing colonoscopy and FIT for CRC outcomes are underway, but results not yet available.
Measurement properties of the incremental step test for people with chronic obstructive pulmonary disease: a cross-sectional study
Objectives
The new incremental step test (IST) is a field test that was developed for people with chronic obstructive pulmonary disease (COPD), based on the characteristics of the incremental shuttle walk test (ISWT); however, its measurement properties still need to be determined. We aimed, first, to assess the construct validity (through the comparison with the ISWT), within-day reliability and measurement error of the IST in people with COPD; and, second, to identify whether the participants have a learning effect in the IST.
Design
Cross-sectional study, conducted according to COnsensus-based Standards for the selection of health status Measurement INstruments guidelines.
Setting
A family health unit in Portugal, April 2022 to June 2023.
Participants and analysis
63 participants (67.5±10.5 years) attended two sessions to perform two IST and two ISWT, separately. Spearman’s correlations were used to compare the best performances between the IST and the ISWT. Intraclass correlation coefficient (ICC2,1) was used for reliability, and the SE of measurement (SEM), minimal detectable change at 95% CI (MDC95) and Bland and Altman 95% limits of agreement (LoA) were used for measurement error. The learning effect was explored with the Wilcoxon signed-rank test.
Results
The IST was significant and strongly correlated with the ISWT (0.72
In persons aged ≥45 y, the mt-sRNA test had 94% sensitivity for colorectal cancer and 46% for advanced adenomas
Annals of Internal Medicine, Ahead of Print.
In persons aged ≥45 y, the mt-sRNA test had 94% sensitivity for colorectal cancer and 46% for advanced adenomas
Annals of Internal Medicine, Ahead of Print.
Sanità, Test Dna fetale inserito nei Lea in Valle d'Aosta
La spesa annua stimata è pari a 220.500 euro
In Zambia picco di infezioni di colera e scarsi vaccini
Condizioni igieniche e piogge eccessive le maggiori cause