Risultati per: Gestione della colite ulcerosa e del morbo di Crohn

Inflammatory bowel disease is a chronic manifestation of dysregulated immune response to the gut microbiota in genetically pre-disposed hosts. Nearly half of patients with Crohn’s disease (CD) develop selective serum IgG response to flagellin proteins expressed by bacteria in the Lachnospiraceae family. This study aimed to identify the binding epitopes of these IgG antibodies and assess their relevance in CD and in homeostasis.

The pathophysiology of Crohn’s-like disease of the ileal pouch-anal anastomosis (CDP) in patients with a history of ulcerative colitis (UC) is unknown. We examined mucosal cells from patients with and without CDP using single cell analyses.

Coinvolge centri specializzati e atenei Bologna, Milano e Padova

New England Journal of Medicine, Volume 391, Issue 3, Page 213-223, July 18, 2024.

This case report describes 2 patients with metastatic Crohn disease who were treated with upadacitinib.