Risultati per: Linee guida ESC/ERS 2022 per la diagnosi e il trattamento dell'ipertensione polmonare

This study examines US trends in the proportion of female applicants and matriculants to residency programs for high-compensation surgical and nonsurgical pipeline specialties during 2008-2022.

This Medical News article is an interview with European Society of Cardiology Vice President Carlos Aguiar, MD, about clinical research highlights from the largest scientific meeting in cardiovascular medicine, held recently in London.

Objectives
To investigate worry about COVID-19 during the pandemic, and whether worry was associated with phase of the pandemic, COVID-19 death and incidence rates, Government interventions (including lockdown and advertising), age, being clinically at-risk, ethnicity, thinking that the Government had put the right measures in place, perceived risk of COVID-19 to self and the UK, and perceived severity of COVID-19.

Design
Secondary analysis of a series of cross-sectional surveys.

Setting
73 online surveys conducted for the English Department of Health and Social Care between 28 January 2020 and 13 April 2022.

Participants
Participants were people aged 16 years and over living in the UK (approximately 2000 per wave).

Primary outcome measures
Our primary outcome was self-reported worry about COVID-19.

Results
Rates of being ‘extremely’ or ‘very’ worried changed over time. Worry increased as infection rates increased and fell during lockdowns, but the association became less obvious over time. Respondents aged 60 years and over were less likely to be worried after the launch of the vaccination campaign, while those who were clinically at-risk or from a minoritised ethnic community were more likely to be worried. Higher worry was associated with higher perceived risk, and higher perceived severity of COVID-19. There was no evidence for an association with agreeing that the Government was putting the right measures in place to prevent the spread of COVID-19. The launch of graphic Government advertising campaigns about COVID-19 had no noticeable effect on levels of public worry.

Conclusions
In future infectious disease outbreaks, spikes in worry may attenuate over time, although some sections of society may experience higher anxiety than others.

Dati Iss, il 66% senza cintura nei sedili posteriori, il 20% non usa il seggiolino per i bambini

Annals of Internal Medicine, Ahead of Print.

Annals of Internal Medicine, Ahead of Print.

Non solo un problema dei bimbi ma “attenzione all’autodiagnosi”

Objective
We assessed the association of early statin initiation with inpatient mortality among hospitalised COVID-19 patients.

Design, setting and participants
This observational study emulated a hypothetical target trial using electronic health records data from Northwestern Medicine Health System, Illinois, 2020–2022. We included patients who were ≥40 years, admitted ≥48 hours for COVID-19 from March 2020 to August 2022 and had no evidence of statin use before admission.

Interventions
Individuals who initiated any statins within 48 hours of admission were compared with individuals who did not initiate statins during this period.

Primary outcome measures
Inpatient mortality at hospital days 7, 14, 21 and 28 were determined using hospital records. Risk differences between exposure groups were calculated using augmented inverse propensity weighting (AIPW) with SuperLearner.

Results
A total of 8893 individuals (24.5% early statin initiators) were included. Early initiators tended to be older, male and have higher comorbidity burdens. Unadjusted day 28 mortality was higher in early initiators (6.0% vs 3.6%). Adjusted analysis showed slightly higher inpatient mortality risk at days 7 (RD: 0.5%, 95% CI: 0.2 to 0.8) and 21 (RD: 0.6%, 95% CI: 0.04 to 1.1), but not days 14 (RD: 0.4%, 95% CI: –0.03 to 0.9) and 28 (RD: 0.4%, 95% CI: –0.2 to 1.1). Sensitivity analyses using alternative modelling approaches showed no difference between groups.

Conclusions
Early statin initiation was not associated with lower mortality contrasting with findings of previous observational studies. Trial emulation helped in identifying and addressing sources of bias incompletely addressed by previous work. Statin use may be indicated for other conditions but not COVID-19.

Per l’86% degli oncologi sono troppe le disparità di accesso alle cure

Per 86% oncologi sono troppe le disparità di accesso alle cure

Il 22 settembre si celebra la Giornata nazionale di informazione

La ricerca sulla comprensione e sulla gestione di questa malattia neurodegenerativa si apre ai fattori di protezione e allo screening con l’intelligenza artificiale