Risultati per: Probiotici: in vivo vs in vitro

In HIV and ID Observations, Dr. Paul Sax looks at a study on masks worn by healthcare workers.

To the Editor We have some comments about the limitations of the CRISTAL trial, which evaluated the effect of aspirin vs enoxaparin on symptomatic VTE in patients undergoing hip or knee arthroplasty.

To the Editor We have some comments about the CRISTAL study, which investigated the effect of aspirin vs enoxaparin on symptomatic venous thromboembolism (VTE) in patients undergoing hip or knee arthroplasty.

This randomized clinical trial compares pulmonary vein isolation (PVI) vs PVI with posterior wall isolation for achieving freedom from atrial arrhythmia in adult patients with persistent atrial fibrillation undergoing first-time catheter ablation in Australia, the UK, and Canada.

To the Editor A recent study showed that aspirin, compared with enoxaparin, resulted in a significantly higher rate of symptomatic VTE within 90 days in patients undergoing hip or knee arthroplasty for osteoarthritis. Mortality from pulmonary embolism after hip and knee arthroplasty has decreased significantly over the past few decades and now remains low regardless of the prophylaxis drug used. Other improvements in perioperative care have played an important role in reducing the mortality rate. In this study, every hospital could provide all patients with pneumatic compression calf devices and compression stockings, which may have contributed to the low incidence of VTE.

In Reply First, we would like to address some of the concerns about the issue of confounding from unmeasured variables (anesthesia type and postoperative rehabilitation) that was mentioned by Dr Chia-Chien Hsu and colleagues. Due to the randomized, crossover design of our study, each participating cluster (hospital) served as its own control. This design provided balancing of baseline variables (Table 1 in the article) and likely also resulted in balancing of unmeasured covariates.

A randomized trial showed no difference in cardiovascular outcomes or mortality.

Annals of Internal Medicine, Ahead of Print.

Annals of Internal Medicine, Ahead of Print.

Annals of Internal Medicine, Ahead of Print.

Annals of Internal Medicine, Ahead of Print.

Annals of Internal Medicine, Ahead of Print.

Annals of Internal Medicine, Ahead of Print.

Annals of Internal Medicine, Ahead of Print.

Annals of Internal Medicine, Ahead of Print.

Annals of Internal Medicine, Ahead of Print.