Risultati per: Trattamento domiciliare di un paziente positivo al virus SARS-Cov-2

This randomized clinical trial evaluates the efficacy of oral nirmatrelvir-ritonavir for treatment of moderate to severe postacute sequelae of SARS-CoV-2 infection of 3 months or longer duration.

To the Editor We read with great interest the study conducted by Schober et al, in which the objective was to assess whether rapid respiratory virus testing in emergency department patients suspected of having acute respiratory infections correlates with reduced antibiotic administration, fewer ancillary tests, shorter emergency department duration, and lower rates of emergency department revisits and hospital admissions, alongside an increase in influenza antiviral therapy. I would like to start by commending the author for adhering to the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) reporting guideline and registering the protocol in the International Prospective Register of Systematic Reviews (PROSPERO), which established a strong foundation for this systematic review. However, when analyzing the research methods, I identified several areas that could further strengthen the study.

In Reply We express our gratitude to Acuña-Rocha for raising 4 important points regarding the methods of our systematic review and meta-analysis of randomized clinical trials on the impact of rapid respiratory virus testing in emergency departments on clinical outcomes.

E’ stata ricoverata in ospedale a Padova

‘Alto rischio’ encefalite equina occidentale. Lockdown serali

Nei giorni scorsi era toccato ad un’altra collega

Objectives
To assess the seroprevalence of infection-acquired SARS-CoV-2 and the mental health of school/daycare staff in the months after reopening of schools in Montreal, Quebec (Canada) in the Fall of 2020 and whether these varied by school and participant characteristics.

Design
A cross-sectional design based on a convenience sample of schools/daycares and staff was used as the originally planned longitudinal design was no longer feasible due to obstacles in recruitment, for example, teacher’s strike.

Setting
Forty-nine schools/daycares in four Montreal neighbourhoods from March to October 2021.

Participants
Three-hundred and sixty-two participants completed both questionnaires and serology tests.

Primary and secondary outcome measures
SARS-CoV-2 seroprevalence and prevalence of anxiety, depression, resilience and burnout/emotional exhaustion.

Results
The seroprevalence estimate made representative to the Quebec population of educators was 8.6% (95% CI 5.2 to 13.0). The adjusted seroprevalence in high school was 20% that of elementary school (aRR=0.20, 95% CI 0.07 to 0.58). Thirty per cent of seropositive staff were exposed to a household member with confirmed COVID-19. Prevalence of high emotional exhaustion/burnout was 35%, 44% and 53% in daycare, elementary school and high school staff, respectively. However, moderate/severe anxiety and depression and low resilience did not exceed 18%. After adjusting for confounders, being very afraid of catching COVID-19 at school was associated with moderate–severe anxiety, moderate–severe depression and high emotional exhaustion (aRR=4.4, 95% CI 2.2 to 8.9; aRR=2.8, 95% CI 1.5 to 5.4; aRR=2.2, 95% CI 1.6 to 3.0, respectively).

Conclusion
The seroprevalence, anxiety and depression among school/daycare staff were comparable to the reported levels in the adult population of Quebec. The prevalence of emotional exhaustion/burnout was high across all school levels and exceeding the average across all occupations in the USA and in teachers in Germany.

Insultata e strattonata, presenta denuncia

Via libera alla commercializzazione di mResvia di Moderna per gli over 60

101 sono nella forma neuro-invasiva,soprattutto in Veneto ed E-R

Annals of Internal Medicine, Ahead of Print.