Risultati per: Linee-guida GOLD 2023,cosa cambia?

Objectives
To investigate the knowledge, attitude and practice (KAP) towards insomnia and sleep hygiene among patients with chronic insomnia.

Design
Web-based cross-sectional survey.

Setting
Shaanxi Provincial People’s Hospital (northwest China) between January 2023 and May 2023.

Participants
Patients with chronic insomnia.

Primary and secondary outcome measures
Demographic characteristics and KAP towards insomnia and sleep hygiene were collected by distributing a questionnaire developed by the authors.

Results
A total of 613 people participated in this study, with a Mean Knowledge Score of 7.63±2.56 (total score of 12), a Mean Attitude Score of 48.39±6.643 (total score of 70) and a Mean Practice Score of 42.37±8.592 (total score of 70). Knowledge was significantly correlated with attitude (r=0.447, p

This study uses data from US retail pharmacies to assess national GLP-1RA dispensing to adolescents and young adults from 2020-2023.

This cohort study evaluates the risk of death in patients hospitalized for COVID-19 or seasonal influenza following the emergence of the JN.1 variant in winter 2023.

Circulation, Volume 149, Issue 24, Page e1413-e1413, June 11, 2024.

Circulation, Volume 149, Issue 24, Page e1411-e1411, June 11, 2024.

Il decreto garantisce che ogni prestazione sia assicurata nei tempi previsti dalle prioirità indicate in ricetta. Ma ci sono anche doveri per i cittadini

We sincerely thank the 878 peer reviewers who completed manuscript reviews for JAMA Oncology in 2023.

L’intervento nasce dopo le polemiche per l’utilizzo all’ospedale Careggi di Firenze del farmaco triptorelina che blocca la pubertà nei minori

We sincerely thank the 657 peer reviewers who completed manuscript reviews for JAMA Dermatology in 2023.

Background
Prosthetic joint infections (PJIs) are a serious negative outcome of arthroplasty with incidence of about 1%. Risk of PJI could depend on local treatment policies and guidelines; no UK-specific risk scoring is currently available.

Objective
To determine a risk quantification model for the development of PJI using electronic health records.

Design
Records in Clinical Practice Research Datalink (CPRD) GOLD and AURUM of patients undergoing hip or knee arthroplasty between January 2007 and December 2014, with linkage to Hospital Episode Statistics and Office of National Statistics, were obtained. Cohorts’ characteristics and risk equations through parametric models were developed and compared between the two databases. Pooled cohort risk equations were determined for the UK population and simplified through stepwise selection.

Results
After applying the inclusion/exclusion criteria, 174 905 joints (1021 developed PJI) were identified in CPRD AURUM and 48 419 joints (228 developed PJI) in CPRD GOLD. Patients undergoing hip or knee arthroplasty in both databases exhibited different sociodemographic characteristics and medical/drug history. However, the quantification of the impact of such covariates (coefficients of parametric models fitted to the survival curves) on the risk of PJI between the two cohorts was not statistically significant. The log-normal model fitted to the pooled cohorts after stepwise selection had a C-statistic >0.7.

Conclusions
The risk prediction tool developed here could help prevent PJI through identifying modifiable risk factors pre-surgery and identifying the patients most likely to benefit from close monitoring/preventive actions. As derived from the UK population, such tool will help the National Health Service reduce the impact of PJI on its resources and patient lives.