Risultati per: Identificati potenziali bersagli per il cancro al pancreas

In Sardegna nel 2021 sono stati ricoverati 262 pazienti

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Bene i primi test. Moltiplicate le ricerche in questa direzione

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Recent advances in single-cell RNA sequencing and bioinformatics have drastically increased our ability to interrogate the cellular composition of traditionally difficult to study organs, such as the pancreas. With the advent of these technologies and approaches, the field has grown, in just a few years, from profiling pancreas disease states to identifying molecular mechanisms of therapy resistance in pancreatic ductal adenocarcinoma, a particularly deadly cancer. Single-cell transcriptomics and related spatial approaches have identified previously undescribed epithelial and stromal cell types and states, how these populations change with disease progression, and potential mechanisms of action which will serve as the basis for designing new therapeutic strategies. Here, we review the recent literature on how single-cell transcriptomic approaches have changed our understanding of pancreas biology and disease progression.

Ricerca del team del National Cancer Centre di Singapore

Children between the ages of 2 and 6 years who used a closed-loop system to manage their type 1 diabetes spent 12% more time—which translated to about 3 hours—with their blood glucose levels within optimal range compared with those who used either an insulin pump or injections, according to a randomized clinical trial that monitored 102 children for 13 weeks. Hypoglycemia levels were similar between the groups, but 1 case of diabetic ketoacidosis occurred in the closed-loop system group.

Studio condotto dall’Istituto Pascale di Napoli