Abstract WMP21: Blood Biomarkers Of Endothelial And Macrocytic Activation Are Associated With Brain White Matter Microstructure In People Living With Hiv On Antiretroviral Treatment.

Stroke, Volume 53, Issue Suppl_1, Page AWMP21-AWMP21, February 1, 2022. Objective:To identify associations between specific serum inflammatory markers and structural white matter integrity as measured on brain diffusion tensor imaging (DTI) in middle-aged people living with HIV (PLWH).Methods:PLWH over 50 years of age residing in New York, NY participated in a cross-sectional study between January and July 2019. Demographic and magnetic resonance imaging data, along with blood samples, were collected. Least absolute shrinkage and selection operator (LASSO) regression was used to identify the most relevant variables associated with brain white matter fractional anisotropy (FA) and mean diffusivity (MD), among seventeen serum inflammatory markers, and control variables (listed in Table 1).Results:A total of 85 PLWH were included in the analysis. Mean age (SD) was 60 (6) years, 48% were men and 78% non-Hispanic black. All were taking antiretroviral therapy at enrollment. Among them, 75% had CD4 count ≥200 cell/mm3and viral load

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Febbraio 2022

Malattie neurodegenerative: la cronicità fra telemedicina e assistenza domiciliare

Live con Daiana Taddeo, MMG, area nazionale Ricerca Simg- Società italiana di medicina generale e delle cure primarie, Luigi Lavorgna, Neurologo Clinica Neurologica – Aou – Università degli Studi della Campania “Luigi Vanvitelli”, responsabile gruppo Digital – Sin, e Paolo Bandiera, Direttore Affari Generali e Advocacy Aism – Associazione italiana sclerosi multipla

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Ottobre 2021