Questo è quello che abbiamo trovato per te
This cross-sectional study compares emergency department use among transgender and gender-diverse as well as cisgender Medicare beneficiaries.
Il 70% dei pazienti oncologici trova informazioni errate sui social
‘Disponibili a essere parte attiva’. Anticorpi per prevenirlo
In una circolare. Secondo le raccomandazioni dell’Ecdc
7,5 mln euro da rete pubblico privata per medicina predittiva
Comunicato del 20/03/2024 n°16
Gli esperti puntano l’attenzione su questi disturbi, spesso sottostimati e che in molti casi vengono trattati con il “fai-da-te”
Objectives
This study aims to identify how real-world data (RWD) have been used in single technology appraisals (STAs) of cancer drugs by the National Institute for Health and Care Excellence (NICE).
Design
Cross-sectional study of NICE technology appraisals of cancer drugs for which guidance was issued between January 2011 and December 2021 (n=229). The appraisals were reviewed following a published protocol to extract the data about the use of RWD. The use of RWD was analysed by reviewing the specific ways in which RWD were used and by identifying different patterns of use.
Primary outcome measure
The number of appraisals where RWD are used in the economic modelling.
Results
Most appraisals used RWD in their economic models. The parametric use of RWD was commonly made in the economic models (76% of the included appraisals), whereas non-parametric use was less common (41%). Despite widespread use of RWD, there was no dominant pattern of use. Three sources of RWD (registries, administrative data, chart reviews) were found across the three important parts of the economic model (choice of comparators, overall survival and volume of treatment).
Conclusions
NICE has had a long-standing interest in the use of RWD in STAs. A systematic review of oncology appraisals suggests that RWD have been widely used in diverse parts of the economic models. Between 2011 and 2021, parametric use was more commonly found in economic models than non-parametric use. Nonetheless, there was no clear pattern in the way these data were used. As each appraisal involves a different decision problem and the ability of RWD to provide the information required for the economic modelling varies, appraisals will continue to differ with respect to their use of RWD.
Da domani nella sede della Fondazione. Da 2 anni boom di domanda
Per la settimana mondiale Italia capofila con il progetto Mnesys
Per la settimana mondiale Italia capofila con il progetto Mnesys
Sono state consegnate 21mila adesioni a petizione
Objectives
This study sought to examine the relationship between Toxoplasma gondii seropositivity and cognitive function in older adults.
Design
An observational cross-sectional study.
Setting
The National Health and Nutrition Examination Survey (NHANES) study took place at participants’ homes and mobile examination centres.
Participants
A total of 2956 older adults aged 60 and above from the NHANES from 2011 to 2014 were included in the study. Exposure of interest: participants had serum Toxoplasma gondii antibody analysed in the laboratory. A value >33 IU/mL was categorised as seropositive for Toxoplasma gondii infection;
Comunicato del 28/02/2024 n°13
