Objectives
To investigate low-grade inflammation in type 2 diabetes and explore associations to clinical aspects as well as microvascular and macrovascular complications.
Design
Cross-sectional analysis.
Setting
The outpatient diabetes clinic at the Department of Endocrinology at Aalborg University Hospital, Denmark.
Participants
100 participants with type 2 diabetes confirmed by a haemoglobin A1c (HbA1c)≥6.5% for a minimum of 1 year and 21 healthy controls.
Outcome measures
Serum levels of 27 inflammation-related biomarkers measured by immunoassay. Associations with microvascular and macrovascular complications, body weight, glycaemic control, medication and sex were investigated in the diabetes cohort.
Results
Serum levels of tumour necrosis factor (TNF)-α and eotaxin were elevated in type 2 diabetes (p