Risultati per: Nota 91

Annals of Internal Medicine, Ahead of Print.

Annals of Internal Medicine, Volume 177, Issue 9, Page JC107, September 2024.

Tra giugno e settembre i medici vedono molto spesso saltare anche i riposi settimanali e l’intervallo delle 11 ore di riposo giornaliero

Stroke, Volume 55, Issue Suppl_1, Page A91-A91, February 1, 2024. Background:Patients with stroke frequently suffer from post-stroke mood disturbances (PSMD) which decrease their quality of life. It remains unclear whether the prevalence of PSMD differs according to stroke subtype. The aim of our study was to investigate PSMD incidence among stroke subtypes in the large, prospective Field Administration of Stroke Therapy – Magnesium (FAST-MAG) Trial.Methods:In the publicly-available FAST-MAG database, we identified all patients with imaging-confirmed diagnoses of ischemic stroke (IS), transient ischemic attack (TIA), and intracerebral hemorrhage (ICH). Data on age, sex, NIHSS at presentation, stroke subtypes, and Stroke Impact Scale (SIS) 64 v3.0 at 90 days were collected. Differences in SIS Emotion Domain scores between IS, TIA, and ICH were assessed using the Mann-Witney U Test.Results:SIS Emotion Domain scores were available in 1239/1370 (90.4%) of patients. Mean age was 68.7 years (SD 13.4), and 41% were female. Median NIHSS was 7.0 (IQR 3-14). 65.3% had IS, 14.3% TIA, and 20.3% ICH. The preponderance of SIS-64 scores were patient-reported (86%) with the remainder completed by a patient proxy (14%). Emotion domain scores at 3 months were: lowest (most abnormal) in ICH patients (median 77.8, IQR 58.3-88.9); intermediate in IS patients (median 83.3, IQR 66.7-94.4); and highest in TIA patients (median 88.9, IQR 72.2-97.2), p

Il 76% con ‘brain fog’. Studio gruppo Ini presentato a Lisbona

A partire dal 27 giugno 2023 è disponibile un aggiornamento dei documenti allegati alla Nota 100 (schede di prescrizione ed elenco dei farmaci)

Crescono lei allerte resilienza, 4 regioni a rischio alto

L’Agenzia Italiana del Farmaco ha aggiornato la Nota 96 (determina AIFA n. 48/2023 pubblicata nella Gazzetta Ufficiale n. 43 del 20 febbraio 2023) sui criteri di appropriatezza prescrittiva della supplementazione con vitamina D e suoi analoghi (colecalciferolo, calcifediolo) per la prevenzione e il trattamento degli stati di carenza nell’adulto

Stroke, Volume 54, Issue Suppl_1, Page A91-A91, February 1, 2023. Objective:To discern effects of early statin treatment on early stroke recurrence in the POINT trial.Background:Benefits of statin therapy in reducing risk of ischemic stroke over the long-term are well-established, but the immediate effects of statin therapy on early stroke recurrence after an initial ischemic event are less clear.Design/Methods:In secondary analysis of the data of the Platelet Oriented Inhibition in New TIA and Minor Ischemic Stroke (POINT) trial, we evaluated the effects of statins on early stroke recurrence within 7 days of randomization using Cox proportional hazard regression analysis. We separately compared the effects in subgroups of subjects on and not on statins prior to the index event.Results:In the POINT trial, most recurrences of ischemic stroke were early, with 175 occurring within 7 days of trial entry, and only 105 occurring over the remainder of the 90 day trial. Overall, 39% were on statin treatment at time of enrollment which increased to 79% by 7 days post-index event. In Cox proportional hazard analysis for stroke recurrence over the 7 day period after index stroke or TIA, statin administration showed no significant effect in subjects not on statin at baseline (Adjusted p=0.34). In contrast, statin use prior to enrollment was associated with decreased hazard of early stroke recurrence (Adjusted H.R. 0.31, p=0.001).Conclusion:In the POINT trial population of patients with minor ischemic stroke or TIA, prior treatment with statins was associated with decreased risk of early stroke recurrence within 7 days following index stroke or TIA. There was no effect of initiating statin treatment in reducing risk of early stroke recurrence.

Monitoraggio settimanale, scorsa settimana 173 casi ogni 100mila

Monitoraggio Iss, 233 casi per 100mila abitanti contro 296