Risultati per: Standard Italiani per la cura del diabete mellito

Piovella (Soi): ‘Dare ai pazienti il massimo della qualità”

Trattamento rapido e tollerato con ridotto impatto estetico

Trattamento rapido e tollerato con ridotto impatto estetico

Studio, aumenta regolazione zuccheri a lungo termine

Stroke, Volume 56, Issue 4, Page 948-956, April 1, 2025. BACKGROUND:Evidence of the cost implications and health outcomes associated with the use of mobile stroke units (MSU) is required to support their utilization. We aimed to evaluate the causal effect of the use of an MSU compared with a standard ambulance on hospitalization costs and 90- to 180-day health outcomes.METHODS:Causal effect estimation was performed using patient-level data from a cohort of patients with stroke in 2018 identified from the Australian Stroke Clinical Registry (Victoria) and Melbourne MSU. These data were linked to Ambulance Victoria and government-held administrative data sets. In total, linked data from 8657 patients were available. Propensity score matching was used to define comparator groups within a target trial framework. Costs included emergency department and hospital admission costs in the first 180 days after stroke. Multivariable regression analyses of the matched data were used to compare costs and outcomes (mortality and modified Rankin Scale) between MSU and standard ambulance groups.RESULTS:The target trial sample included 96 patients transported by the MSU (intervention) and 198 patients transported by standard ambulance services (control). Of these, the mean age was 76 years and 157 (53%) were men. A greater proportion of patients received mechanical thrombectomy in the intervention group than the control group (40% versus 23%;P

Con un prelievo, in Italia colpisce 20.000 bambini e adolescenti

Optimal treat-to-target strategies for Crohn’s disease (CD) are still being sought. We examined the value of video capsule endoscopy (VCE) to guide proactive treat-to-target optimization in CD.

Invia notifiche tramite app in caso di dosi dimenticate

Esperta, allo studio il ruolo della neuroinfiammazione

Con il World Obesity Day parte un’area di approfondimenti

This Viewpoint outlines the importance of and known barriers to making patient-reported outcome (PRO) collection the standard of care in oncology.

Barbara, ‘stress e alimentazione influenzano suo benessere’

Uniamo: ‘Necessario investire sulla ricerca a 360 gradi’

Introduction
Children having surgery, and their parents, commonly have anxiety in the preoperative period, and this may impact longer-term health and quality of life. Psychological preparation can be expensive and time-consuming, and the type and effectiveness of preparatory interventions are variable. The aim of this randomised controlled trial (RCT) is to evaluate the clinical effectiveness of a preoperative smartphone psychological preparation application with virtual reality (VR) capability (the ‘Little Journey app’ (LJ)), at reducing anxiety and its sequelae in children and their carers.

Methods and analysis
Multicentre, assessor-blinded, two-armed, parallel group, RCT in children aged between 3 and 12 years, undergoing ambulatory surgery and receiving their first general anaesthetic. Randomisation is one-to-one between an intervention and a control arm. Participants in the intervention arm are provided with access to the LJ app and a low-cost cardboard VR headset (to be used with a smartphone) to use in the weeks leading up to their operation. Children in the control arm receive the same VR headset and suggestions of unrelated VR games to play, but no access to the LJ app. To improve accessibility, smart devices are provided to children whose families do not have a smart phone, and the app content has been translated from English into multiple languages. Both groups receive standard perioperative care at the hospital where they are having treatment. The primary outcome measure is the modified Yale Preoperative Anxiety Scale-Short Form applied by independent blinded observers, immediately before induction of general anaesthesia. Secondary outcomes include process measures, psychological and socioeconomic outcomes for both children and parents/carers. The planned sample size was 304 participants, including an anticipated 15% attrition rate. An interim analysis was conducted when the trial was temporarily paused because of the COVID-19 pandemic, at which point 119 participants had been recruited. The trial steering committee and data monitoring committee recommended continuation of the trial, but the sample size was increased to 596 to account for differences between the previously anticipated and actual outcomes of recruited participants.

Ethics and dissemination
The study was approved by Surrey Borders—Research Ethics Committee 251219, and all participating sites were in England. Results will be presented in academic manuscripts and presentations and summarised for diverse audiences (including clinicians and patients/public) in podcasts, infographics and other multimedia formats.

Trial registration number
NCT03797716.

Barbara, ‘stress e alimentazione influenzano suo benessere’